ENSMUSG00000031402


Mus musculus

Features
Gene ID: ENSMUSG00000031402
  
Biological name :Mpp1
  
Synonyms : membrane protein, palmitoylated / Mpp1 / P70290
  
Possible biological names infered from orthology : membrane palmitoylated protein 1 / Q00013
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A7.3
Gene start: 75109733
Gene end: 75131016
  
Corresponding Affymetrix probe sets: 10605370 (MoGene1.0st)   1423243_at (Mouse Genome 430 2.0 Array)   1450919_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033775
Ensembl peptide - ENSMUSP00000118693
Ensembl peptide - ENSMUSP00000117003
Ensembl peptide - ENSMUSP00000116897
Ensembl peptide - ENSMUSP00000116401
Ensembl peptide - ENSMUSP00000109726
Ensembl peptide - ENSMUSP00000109725
NCBI entrez gene - 17524     See in Manteia.
MGI - MGI:105941
RefSeq - NM_008621
RefSeq Peptide - NP_032647
swissprot - B7ZCL9
swissprot - B7ZCL8
swissprot - A2AN84
swissprot - P70290
swissprot - D6RFD5
swissprot - Q542P4
swissprot - B7ZCM1
swissprot - B7ZCM0
Ensembl - ENSMUSG00000031402
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mpp1ENSDARG00000105287Danio rerio
 MPP1ENSGALG00000005071Gallus gallus
 MPP1ENSG00000130830Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101256
Mpp2 / Q9WV34 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q14168* / membrane palmitoylated protein 2*ENSMUSG0000001731440
Mpp6 / Q9JLB0 / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Q9NZW5* / membrane palmitoylated protein 6*ENSMUSG0000003838840
Mpp7 / MAGUK p55 subfamily member 7 isoform 2 / Q5T2T1* / membrane palmitoylated protein 7*ENSMUSG0000005744034
Mpp4 / Q6P7F1 / MAGUK p55 subfamily member 4 / Q96JB8* / membrane palmitoylated protein 4*ENSMUSG0000007955031
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237330
Mpp5 / Q9JLB2 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Q8N3R9* / membrane palmitoylated protein 5*ENSMUSG0000002111229
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088127
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257226
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088625
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277025
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051619
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178218
Tjp3 / tight junction protein 3 / O95049*ENSMUSG0000003491718
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481218
Guk1 / guanylate kinase 1 / Q16774*ENSMUSG0000002044412


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035475  MPP1, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090022 regulation of neutrophil chemotaxis IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030863 cortical cytoskeleton IDA
 cellular_componentGO:0032420 stereocilium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nfkb2Lym1/Nfkb2Lym1
Genetic Background: involves: BALB/c

 MP:0002463 abnormal neutrophil physiology "abnormal function of these granular leukocytes, which stain with neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nfkb2Lym1/Nfkb2Lym1
Genetic Background: involves: BALB/c

 MP:0008720 impaired neutrophil migration "defect in the ability of neutrophils to move along a chemotactic gradient" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nfkb2Lym1/Nfkb2Lym1
Genetic Background: involves: BALB/c

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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