ENSMUSG00000079550


Mus musculus

Features
Gene ID: ENSMUSG00000079550
  
Biological name :Mpp4
  
Synonyms : MAGUK p55 subfamily member 4 / Mpp4 / Q6P7F1
  
Possible biological names infered from orthology : membrane palmitoylated protein 4 / Q96JB8
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C1.3
Gene start: 59120935
Gene end: 59163389
  
Corresponding Affymetrix probe sets: 10354955 (MoGene1.0st)   1417783_at (Mouse Genome 430 2.0 Array)   1460368_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109914
Ensembl peptide - ENSMUSP00000140957
Ensembl peptide - ENSMUSP00000140352
Ensembl peptide - ENSMUSP00000070711
Ensembl peptide - ENSMUSP00000077914
NCBI entrez gene - 227157     See in Manteia.
MGI - MGI:2386681
RefSeq - NM_145143
RefSeq - NM_001164682
RefSeq Peptide - NP_001158154
RefSeq Peptide - NP_660125
swissprot - Q6P7F1
swissprot - A0A087WQU9
swissprot - K3W4N9
swissprot - D3Z0G8
Ensembl - ENSMUSG00000079550
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MPP4 (1 of many)ENSDARG00000076872Danio rerio
 mpp4aENSDARG00000058222Danio rerio
 si:ch211-222n4.6ENSDARG00000009386Danio rerio
 MPP4ENSGALG00000008398Gallus gallus
 MPP4ENSG00000082126Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mpp7 / MAGUK p55 subfamily member 7 isoform 2 / Q5T2T1* / membrane palmitoylated protein 7*ENSMUSG0000005744037
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237335
Mpp5 / Q9JLB2 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Q8N3R9* / membrane palmitoylated protein 5*ENSMUSG0000002111230
Mpp6 / Q9JLB0 / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Q9NZW5* / membrane palmitoylated protein 6*ENSMUSG0000003838827
Mpp2 / Q9WV34 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q14168* / membrane palmitoylated protein 2*ENSMUSG0000001731426
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257224
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101224
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277024
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088123
Mpp1 / P70290 / membrane protein, palmitoylated / Q00013* / membrane palmitoylated protein 1*ENSMUSG0000003140222
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088621
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178219
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481216
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051616
Tjp3 / tight junction protein 3 / O95049*ENSMUSG0000003491715
Guk1 / guanylate kinase 1 / Q16774*ENSMUSG0000002044412


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR014775  L27 domain, C-terminal
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035600  MPP4, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily
 IPR036892  L27 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035418 protein localization to synapse IMP
 cellular_componentGO:0000139 Golgi membrane IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016328 lateral plasma membrane IDA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0042734 presynaptic membrane IDA
 cellular_componentGO:0044316 cone cell pedicle IDA
 cellular_componentGO:0044317 rod spherule IDA
 cellular_componentGO:0045178 basal part of cell IDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001004 abnormal photoreceptor morphology "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Aqp2tm1(cre)Blyg/Aqp2tm1(cre)Blyg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Kat6atm1Avo/Kat6a+
Genetic Background: involves: 129 * BALB/c * FVB/N

 MP:0003950 abnormal plasma membrane morphology "anomalous structure of the semipermeable membrane that encloses the cytoplasm of a cell" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Kat6atm1Avo/Kat6a+
Genetic Background: involves: 129 * BALB/c * FVB/N

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Aqp2tm1(cre)Blyg/Aqp2tm1(cre)Blyg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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