ENSMUSG00000038388


Mus musculus

Features
Gene ID: ENSMUSG00000038388
  
Biological name :Mpp6
  
Synonyms : membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Mpp6 / Q9JLB0
  
Possible biological names infered from orthology : membrane palmitoylated protein 6 / Q9NZW5
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B2.3
Gene start: 50110241
Gene end: 50198939
  
Corresponding Affymetrix probe sets: 10538253 (MoGene1.0st)   1439263_at (Mouse Genome 430 2.0 Array)   1441546_at (Mouse Genome 430 2.0 Array)   1449348_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125880
Ensembl peptide - ENSMUSP00000144737
Ensembl peptide - ENSMUSP00000129355
Ensembl peptide - ENSMUSP00000129004
Ensembl peptide - ENSMUSP00000038772
Ensembl peptide - ENSMUSP00000039314
NCBI entrez gene - 56524     See in Manteia.
MGI - MGI:1927340
RefSeq - NM_001164733
RefSeq - NM_001164734
RefSeq - NM_019939
RefSeq Peptide - NP_001158206
RefSeq Peptide - NP_064323
RefSeq Peptide - NP_001158205
swissprot - Q9JLB0
swissprot - E9PWC5
swissprot - B9EHZ5
swissprot - Q3UN60
swissprot - E9Q2R8
Ensembl - ENSMUSG00000038388
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mpp6aENSDARG00000056892Danio rerio
 mpp6bENSDARG00000029761Danio rerio
 MPP6ENSGALG00000010988Gallus gallus
 MPP6ENSG00000105926Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mpp2 / Q9WV34 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q14168* / membrane palmitoylated protein 2*ENSMUSG0000001731467
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101241
Mpp7 / MAGUK p55 subfamily member 7 isoform 2 / Q5T2T1* / membrane palmitoylated protein 7*ENSMUSG0000005744035
Mpp1 / P70290 / membrane protein, palmitoylated / Q00013* / membrane palmitoylated protein 1*ENSMUSG0000003140234
Mpp5 / Q9JLB2 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Q8N3R9* / membrane palmitoylated protein 5*ENSMUSG0000002111233
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237333
Mpp4 / Q6P7F1 / MAGUK p55 subfamily member 4 / Q96JB8* / membrane palmitoylated protein 4*ENSMUSG0000007955031
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257227
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088127
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277026
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088626
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178218
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481218
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051617
Tjp3 / tight junction protein 3 / O95049*ENSMUSG0000003491716
Guk1 / guanylate kinase 1 / Q16774*ENSMUSG0000002044413


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR014775  L27 domain, C-terminal
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035603  MPP6, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily
 IPR036892  L27 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046037 GMP metabolic process IEA
 biological_processGO:0046710 GDP metabolic process IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0004385 guanylate kinase activity ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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