ENSDARG00000003902


Danio rerio

Features
Gene ID: ENSDARG00000003902
  
Biological name :ctsl.1
  
Synonyms : cathepsin L.1 / ctsl.1
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 27456804
Gene end: 27461321
  
Corresponding Affymetrix probe sets: Dr.15507.1.S1_at (Zebrafish Array)   Dr.15507.2.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000021632
Ensembl peptide - ENSDARP00000129742
Ensembl peptide - ENSDARP00000146326
Ensembl peptide - ENSDARP00000151690
NCBI entrez gene - 436641     See in Manteia.
RefSeq - XM_005158777
RefSeq Peptide - NP_001002368
swissprot - X1WHM9
swissprot - Q6DHT0
ZFIN ID - ZDB-GENE-040718-61
Ensembl - ENSDARG00000003902
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ctsla / cathepsin LaENSDARG0000000783653
ctsll / cathepsin L, like / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / CTSV* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q...ENSDARG0000001170153
si:dkey-269i1.4 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / B...ENSDARG0000009574451
si:dkey-269i1.4 / CTSL* / CTSV* / O60911* / P07711* / cathepsin V* / cathepsin L*ENSDARG0000010083351
si:dkey-239j18.3 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / ...ENSDARG0000008980651
ctslb / cathepsin Lb / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / CTSV* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q9JI81...ENSDARG0000003917351
si:dkey-26g8.4 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / BC...ENSDARG0000008765151
ctslb / cathepsin Lb / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / CTSV* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q9JI81...ENSDARG0000007430651
si:dkey-26g8.5 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / BC...ENSDARG0000008975050
zgc:174153 / Cts8* / Cts3* / Cts6* / Cts7* / Ctsj* / CTSL* / Ctsm* / Ctsq* / Ctsr* / CTSV* / Q9JIA9* / O60911* / Ctsll3* / Q9R014* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JI81* / BC0516...ENSDARG0000007937650
zgc:174154 / Cts8* / Cts3* / Cts6* / Cts7* / Ctsj* / CTSL* / Ctsm* / Ctsq* / Ctsr* / CTSV* / Q9JIA9* / O60911* / Ctsll3* / Q9R014* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JI81* / BC0516...ENSDARG0000007552750
MGC174155 / Cathepsin L1-like / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / Cts3* / CTSV* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0*...ENSDARG0000009507250
zgc:174855 / Cts8* / Cts3* / Cts6* / Cts7* / Ctsj* / CTSL* / Ctsm* / Ctsq* / Ctsr* / CTSV* / Q9JIA9* / O60911* / Ctsll3* / Q9R014* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JI81* / BC0516...ENSDARG0000009455950
si:dkey-239j18.2 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / ...ENSDARG0000009525450
ctss2.2 / cathepsin S, ortholog 2, tandem duplicate 2 / CTSS* / O70370* / P25774* / cathepsin S*ENSDARG0000001377148
ctss2.1 / cathepsin S, ortholog2, tandem duplicate 1 / CTSS* / O70370* / P25774* / cathepsin S*ENSDARG0000007465645
cts12 / cathepsin 12ENSDARG0000004275344
ctsk / cathepsin K / P43235* / P55097*ENSDARG0000004025143
ctss1 / cathepsin S, ortholog 1ENSDARG0000003694042
zgc:110239ENSDARG0000007766440


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005764 lysosome IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009141 macrophage macrophage morphology , abnormal
macrophage lysosome accumulation macrophage , abnormal
macrophage myeloid leukocyte migration process quality , abnormal
macrophage myeloid leukocyte migration decreased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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