Manteia

ENSDARG00000094559

Danio rerio

Features

Gene ID:	ENSDARG00000094559

Biological name :	zgc:174855

Synonyms :	zgc:174855

Possible biological names infered from orthology :	4930486L24Rik / BC051665 / cathepsin 3 / cathepsin 6 / cathepsin 7 / cathepsin 8 / cathepsin J / cathepsin L / cathepsin L-like 3 / cathepsin M / cathepsin Q / cathepsin R / cathepsin V / cDNA sequence BC051665 / CT030254.2 / Cts3 / Cts6 / Cts7 / Cts8 / Ctsj / CTSL / Ctsll3 / Ctsm / Ctsq / Ctsr / CTSV / O60911 / P06797 / P07711 / Q80UB0 / Q91ZF2 / Q9JI81 / Q9JIA9 / Q9R014 / Testin-2 Testin-1

Species:	Danio rerio

Chr. number:	12
Strand:	-1
Band:
Gene start:	16938807
Gene end:	16941319

Corresponding Affymetrix probe sets:	Dr.25683.1.S1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000098360 NCBI entrez gene - 569326 See in Manteia. RefSeq - NM_001103122 RefSeq Peptide - NP_001096592 swissprot - A7MCR6 ZFIN ID - ZDB-GENE-071004-74 Ensembl - ENSDARG00000094559

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CTSV	ENSGALG00000012610	Gallus gallus
CTSL	ENSG00000135047	Homo sapiens
CTSV	ENSG00000136943	Homo sapiens
BC051665	ENSMUSG00000042243	Mus musculus
CT030254.2	ENSMUSG00000114904	Mus musculus
Cts3	ENSMUSG00000074870	Mus musculus
Cts6	ENSMUSG00000021441	Mus musculus
Cts7	ENSMUSG00000021440	Mus musculus
Cts8	ENSMUSG00000057446	Mus musculus
Ctsj	ENSMUSG00000055298	Mus musculus
Ctsl	ENSMUSG00000021477	Mus musculus
Ctsll3	ENSMUSG00000056728	Mus musculus
Ctsm	ENSMUSG00000074871	Mus musculus
Ctsq	ENSMUSG00000021439	Mus musculus
Ctsr	ENSMUSG00000055679	Mus musculus
Q80UB0	ENSMUSG00000050345	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
zgc:174154 / Cts8* / Cts3* / Cts6* / Cts7* / Ctsj* / CTSL* / Ctsm* / Ctsq* / Ctsr* / CTSV* / Q9JIA9* / O60911* / Ctsll3* / Q9R014* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JI81* / BC0516...	ENSDARG00000075527	99
MGC174155 / Cathepsin L1-like / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / Cts3* / CTSV* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0*...	ENSDARG00000095072	98
si:dkey-26g8.5 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / BC...	ENSDARG00000089750	98
si:dkey-26g8.4 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / BC...	ENSDARG00000087651	97
si:dkey-239j18.2 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / ...	ENSDARG00000095254	97
si:dkey-269i1.4 / CTSL* / CTSV* / O60911* / P07711* / cathepsin V* / cathepsin L*	ENSDARG00000100833	96
zgc:174153 / Cts8* / Cts3* / Cts6* / Cts7* / Ctsj* / CTSL* / Ctsm* / Ctsq* / Ctsr* / CTSV* / Q9JIA9* / O60911* / Ctsll3* / Q9R014* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JI81* / BC0516...	ENSDARG00000079376	96
si:dkey-239j18.3 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / ...	ENSDARG00000089806	96
ctslb / cathepsin Lb / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / CTSV* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q9JI81...	ENSDARG00000039173	96
ctslb / cathepsin Lb / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / CTSV* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q9JI81...	ENSDARG00000074306	96
si:dkey-269i1.4 / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts7* / Cts3* / Cts6* / CTSV* / Q9JI81* / Q9R014* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q91ZF2* / Q9JIA9* / B...	ENSDARG00000095744	96
ctsll / cathepsin L, like / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / CTSV* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q...	ENSDARG00000011701	77
ctsla / cathepsin La	ENSDARG00000007836	68
ctsl.1 / cathepsin L.1	ENSDARG00000003902	50
ctsk / cathepsin K / P43235* / P55097*	ENSDARG00000040251	47
ctss2.2 / cathepsin S, ortholog 2, tandem duplicate 2 / CTSS* / O70370* / P25774* / cathepsin S*	ENSDARG00000013771	46
ctss2.1 / cathepsin S, ortholog2, tandem duplicate 1 / CTSS* / O70370* / P25774* / cathepsin S*	ENSDARG00000074656	45
cts12 / cathepsin 12	ENSDARG00000042753	45
ctss1 / cathepsin S, ortholog 1	ENSDARG00000036940	41
ctsh / cathepsin H / P09668* / P49935*	ENSDARG00000041108	39

Protein motifs (from Interpro)

Interpro ID	Name
IPR000169	Cysteine peptidase, cysteine active site
IPR000668	Peptidase C1A, papain C-terminal
IPR013128	Peptidase C1A
IPR013201	Cathepsin propeptide inhibitor domain (I29)
IPR025660	Cysteine peptidase, histidine active site
IPR025661	Cysteine peptidase, asparagine active site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006508	proteolysis	IEA
biological_process	GO:0051603	proteolysis involved in cellular protein catabolic process	IBA
cellular_component	GO:0005615	extracellular space	IBA
cellular_component	GO:0005764	lysosome	IBA
molecular_function	GO:0004197	cysteine-type endopeptidase activity	IBA
molecular_function	GO:0008233	peptidase activity	IEA
molecular_function	GO:0008234	cysteine-type peptidase activity	IEA
molecular_function	GO:0016787	hydrolase activity	IEA

Pathways (from Reactome)

Pathway description

Collagen degradation

Degradation of the extracellular matrix

Activation of Matrix Metalloproteinases

Trafficking and processing of endosomal TLR

Assembly of collagen fibrils and other multimeric structures

MHC class II antigen presentation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr