ENSGALG00000012610


Gallus gallus

Features
Gene ID: ENSGALG00000012610
  
Biological name :CTSV
  
Synonyms : CTSV
  
Possible biological names infered from orthology : 4930486L24Rik / BC051665 / cathepsin 3 / cathepsin 6 / cathepsin 7 / cathepsin 8 / cathepsin J / cathepsin L / cathepsin L-like 3 / cathepsin M / cathepsin Q / cathepsin R / cathepsin V / cDNA sequence BC051665 / CT030254.2 / Cts3 / Cts6 / Cts7 / Cts8 / Ctsj / CTSL / Ctsll3 / Ctsm / Ctsq / Ctsr / O60911 / P06797 / P07711 / Q80UB0 / Q91ZF2 / Q9JI81 / Q9JIA9 / Q9R014 / Testin-2 Testin-1
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 41408607
Gene end: 41414029
  
Corresponding Affymetrix probe sets: Gga.523.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020559
Ensembl peptide - ENSGALP00000062789
Ensembl peptide - ENSGALP00000059519
NCBI entrez gene - 427466     See in Manteia.
RefSeq - NM_001168009
RefSeq Peptide - NP_001161481
swissprot - A0A1L1RVC8
swissprot - A0A1L1RL78
swissprot - F1NYJ1
Ensembl - ENSGALG00000012610
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctslbENSDARG00000039173Danio rerio
 ctslbENSDARG00000074306Danio rerio
 ctsllENSDARG00000011701Danio rerio
 MGC174155ENSDARG00000095072Danio rerio
 si:dkey-239j18.2ENSDARG00000095254Danio rerio
 si:dkey-239j18.3ENSDARG00000089806Danio rerio
 si:dkey-269i1.4ENSDARG00000100833Danio rerio
 si:dkey-269i1.4ENSDARG00000095744Danio rerio
 si:dkey-26g8.4ENSDARG00000087651Danio rerio
 si:dkey-26g8.5ENSDARG00000089750Danio rerio
 zgc:174153ENSDARG00000079376Danio rerio
 zgc:174154ENSDARG00000075527Danio rerio
 zgc:174855ENSDARG00000094559Danio rerio
 CTSLENSG00000135047Homo sapiens
 CTSVENSG00000136943Homo sapiens
 BC051665ENSMUSG00000042243Mus musculus
 CT030254.2ENSMUSG00000114904Mus musculus
 Cts3ENSMUSG00000074870Mus musculus
 Cts6ENSMUSG00000021441Mus musculus
 Cts7ENSMUSG00000021440Mus musculus
 Cts8ENSMUSG00000057446Mus musculus
 CtsjENSMUSG00000055298Mus musculus
 CtslENSMUSG00000021477Mus musculus
 Ctsll3ENSMUSG00000056728Mus musculus
 CtsmENSMUSG00000074871Mus musculus
 CtsqENSMUSG00000021439Mus musculus
 CtsrENSMUSG00000055679Mus musculus
 Q80UB0ENSMUSG00000050345Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSS / cathepsin S precursor / O70370* / P25774* / cathepsin S*ENSGALG0000000077549
ENSGALG0000000425248
CTSK / cathepsin K / P43235* / P55097*ENSGALG0000002814745
ENSGALG0000001340939
CTSH / cathepsin H / P09668* / P49935*ENSGALG0000003355737
ENSGALG0000002983335


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005764 lysosome IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017183 MMP13 / collagenase 3 precursor / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*  / reaction
 ENSGALG00000012610 CTSV / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q9JI81* / BC051665* / CT030254...  / complex






 

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contact: otassy@igbmc.fr