ENSGALG00000033557


Gallus gallus

Features
Gene ID: ENSGALG00000033557
  
Biological name :CTSH
  
Synonyms : cathepsin H / CTSH
  
Possible biological names infered from orthology : P09668 / P49935
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 19950725
Gene end: 19956592
  
Corresponding Affymetrix probe sets: Gga.7040.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047581
Ensembl peptide - ENSGALP00000051767
RefSeq - XM_015292196
swissprot - A0A1D5P4H3
swissprot - A0A1D5PG47
Ensembl - ENSGALG00000033557
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctshENSDARG00000041108Danio rerio
 CTSHENSG00000103811Homo sapiens
 CtshENSMUSG00000032359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSV / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q9JI81* / BC051665* / CT030254...ENSGALG0000001261040
CTSK / cathepsin K / P43235* / P55097*ENSGALG0000002814738
CTSS / cathepsin S precursor / O70370* / P25774* / cathepsin S*ENSGALG0000000077538
ENSGALG0000001340935
ENSGALG0000000425235
ENSGALG0000002983334


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001913 T cell mediated cytotoxicity IEA
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002764 immune response-regulating signaling pathway IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IEA
 biological_processGO:0010813 neuropeptide catabolic process IEA
 biological_processGO:0010815 bradykinin catabolic process IEA
 biological_processGO:0010952 positive regulation of peptidase activity IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031638 zymogen activation IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0033619 membrane protein proteolysis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043129 surfactant homeostasis IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0060448 dichotomous subdivision of terminal units involved in lung branching IEA
 biological_processGO:0070371 ERK1 and ERK2 cascade IEA
 biological_processGO:0097067 cellular response to thyroid hormone stimulus IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0097208 alveolar lamellar body IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process IEA
 molecular_functionGO:0016505 peptidase activator activity involved in apoptotic process IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030108 HLA-A specific activating MHC class I receptor activity IEA
 molecular_functionGO:0070324 thyroid hormone binding IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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