ENSGALG00000000775


Gallus gallus

Features
Gene ID: ENSGALG00000000775
  
Biological name :CTSS
  
Synonyms : cathepsin S precursor / CTSS
  
Possible biological names infered from orthology : cathepsin S / O70370 / P25774
  
Species: Gallus gallus
  
Chr. number: 25
Strand: -1
Band:
Gene start: 2580940
Gene end: 2585553
  
Corresponding Affymetrix probe sets: Gga.6025.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001120
NCBI entrez gene - 425657     See in Manteia.
RefSeq - NM_001031345
RefSeq - XM_015280007
RefSeq - XM_015280008
RefSeq Peptide - NP_001026516
swissprot - H9KYW5
Ensembl - ENSGALG00000000775
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctss2.1ENSDARG00000074656Danio rerio
 ctss2.2ENSDARG00000013771Danio rerio
 CTSSENSG00000163131Homo sapiens
 CtssENSMUSG00000038642Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSV / Ctsr* / Ctsq* / Ctsm* / CTSL* / Ctsj* / Cts8* / Cts6* / Cts7* / Cts3* / Q91ZF2* / Q9R014* / Q9JIA9* / Ctsll3* / O60911* / P06797* / P07711* / Q80UB0* / Q9JI81* / BC051665* / CT030254...ENSGALG0000001261053
CTSK / cathepsin K / P43235* / P55097*ENSGALG0000002814748
ENSGALG0000000425247
ENSGALG0000001340939
CTSH / cathepsin H / P09668* / P49935*ENSGALG0000003355738
ENSGALG0000002983336


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0010447 response to acidic pH IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0019882 antigen processing and presentation IBA
 biological_processGO:0030574 collagen catabolic process IEA
 biological_processGO:0034769 basement membrane disassembly IEA
 biological_processGO:0048002 antigen processing and presentation of peptide antigen IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 biological_processGO:0097067 cellular response to thyroid hormone stimulus IEA
 biological_processGO:2001259 positive regulation of cation channel activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0001968 fibronectin binding IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043236 laminin binding IEA
 molecular_functionGO:0043394 proteoglycan binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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