ENSMUSG00000042243


Mus musculus

Features
Gene ID: ENSMUSG00000042243
  
Biological name :BC051665
  
Synonyms : BC051665 / cDNA sequence BC051665
  
Possible biological names infered from orthology : cathepsin L / CTSL / P07711
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B2
Gene start: 60781887
Gene end: 60786364
  
Corresponding Affymetrix probe sets: 10409840 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000026078
NCBI entrez gene - 218275     See in Manteia.
MGI - MGI:2682300
RefSeq - NM_199148
RefSeq - XM_011244513
RefSeq Peptide - NP_954599
swissprot - E9Q623
Ensembl - ENSMUSG00000042243
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctslbENSDARG00000039173Danio rerio
 ctslbENSDARG00000074306Danio rerio
 ctsllENSDARG00000011701Danio rerio
 MGC174155ENSDARG00000095072Danio rerio
 si:dkey-239j18.2ENSDARG00000095254Danio rerio
 si:dkey-239j18.3ENSDARG00000089806Danio rerio
 si:dkey-269i1.4ENSDARG00000095744Danio rerio
 si:dkey-269i1.4ENSDARG00000100833Danio rerio
 si:dkey-26g8.4ENSDARG00000087651Danio rerio
 si:dkey-26g8.5ENSDARG00000089750Danio rerio
 zgc:174153ENSDARG00000079376Danio rerio
 zgc:174154ENSDARG00000075527Danio rerio
 zgc:174855ENSDARG00000094559Danio rerio
 CTSVENSGALG00000012610Gallus gallus
 CTSLENSG00000135047Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ctsll3 / cathepsin L-like 3 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005672883
Ctsl / P06797 / cathepsin L / CTSV* / O60911* / cathepsin V*ENSMUSG0000002147762
Q80UB0 / 4930486L24Rik / Testin-2 Testin-1 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005034562
Ctsm / cathepsin M / CTSL* / P07711* / cathepsin L*ENSMUSG0000007487157
Cts8 / Q9JI81 / cathepsin 8 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005744657
Ctsj / Q9R014 / cathepsin J / CTSL* / P07711* / cathepsin L*ENSMUSG0000005529855
Ctsr / Q9JIA9 / cathepsin R / CTSL* / P07711* / cathepsin L*ENSMUSG0000005567954
Cts6 / cathepsin 6 / CTSL* / P07711* / cathepsin L*ENSMUSG0000002144153
Cts3 / cathepsin 3 / CTSL* / P07711* / cathepsin L*ENSMUSG0000007487052
Cts7 / Q91ZF2 / cathepsin 7 / CTSL* / P07711* / cathepsin L*ENSMUSG0000002144051
Ctsq / cathepsin Q / CTSL* / P07711* / cathepsin L*ENSMUSG0000002143951
Ctss / O70370 / cathepsin S / P25774*ENSMUSG0000003864247
Ctsk / P55097 / cathepsin K / P43235*ENSMUSG0000002811145
Ctsf / Q9R013 / cathepsin F / Q9UBX1*ENSMUSG0000008328235
Ctsh / P49935 / cathepsin H / P09668*ENSMUSG0000003235935
Ctsw / P56203 / cathepsin W / P56202*ENSMUSG0000002491028
CT030254.2 / CTSL* / P07711* / cathepsin L*ENSMUSG0000011490420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005764 lysosome IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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