ENSMUSG00000021440


Mus musculus

Features
Gene ID: ENSMUSG00000021440
  
Biological name :Cts7
  
Synonyms : cathepsin 7 / Cts7 / Q91ZF2
  
Possible biological names infered from orthology : cathepsin L / CTSL / P07711
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B2
Gene start: 61352461
Gene end: 61358197
  
Corresponding Affymetrix probe sets: 10409934 (MoGene1.0st)   1447142_at (Mouse Genome 430 2.0 Array)   1451933_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000153508
Ensembl peptide - ENSMUSP00000153603
Ensembl peptide - ENSMUSP00000021892
Ensembl peptide - ENSMUSP00000153003
NCBI entrez gene - 56092     See in Manteia.
MGI - MGI:1860262
RefSeq - NM_019539
RefSeq - XM_006517297
RefSeq - NM_001359387
RefSeq Peptide - NP_001346316
RefSeq Peptide - NP_062412
swissprot - A0A286YCI3
swissprot - Q91ZF2
swissprot - A0A286YDP3
Ensembl - ENSMUSG00000021440
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctslbENSDARG00000039173Danio rerio
 ctslbENSDARG00000074306Danio rerio
 ctsllENSDARG00000011701Danio rerio
 MGC174155ENSDARG00000095072Danio rerio
 si:dkey-239j18.2ENSDARG00000095254Danio rerio
 si:dkey-239j18.3ENSDARG00000089806Danio rerio
 si:dkey-269i1.4ENSDARG00000095744Danio rerio
 si:dkey-269i1.4ENSDARG00000100833Danio rerio
 si:dkey-26g8.4ENSDARG00000087651Danio rerio
 si:dkey-26g8.5ENSDARG00000089750Danio rerio
 zgc:174153ENSDARG00000079376Danio rerio
 zgc:174154ENSDARG00000075527Danio rerio
 zgc:174855ENSDARG00000094559Danio rerio
 CTSVENSGALG00000012610Gallus gallus
 CTSLENSG00000135047Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ctsr / Q9JIA9 / cathepsin R / CTSL* / P07711* / cathepsin L*ENSMUSG0000005567956
Ctsm / cathepsin M / CTSL* / P07711* / cathepsin L*ENSMUSG0000007487156
Cts8 / Q9JI81 / cathepsin 8 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005744655
Cts6 / cathepsin 6 / CTSL* / P07711* / cathepsin L*ENSMUSG0000002144155
Cts3 / cathepsin 3 / CTSL* / P07711* / cathepsin L*ENSMUSG0000007487053
Ctsj / Q9R014 / cathepsin J / CTSL* / P07711* / cathepsin L*ENSMUSG0000005529853
Ctsq / cathepsin Q / CTSL* / P07711* / cathepsin L*ENSMUSG0000002143952
Ctsll3 / cathepsin L-like 3 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005672852
BC051665 / cDNA sequence BC051665 / CTSL* / P07711* / cathepsin L*ENSMUSG0000004224351
Ctsl / P06797 / cathepsin L / CTSV* / O60911* / cathepsin V*ENSMUSG0000002147750
Q80UB0 / 4930486L24Rik / Testin-2 Testin-1 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005034548
Ctss / O70370 / cathepsin S / P25774*ENSMUSG0000003864241
Ctsk / P55097 / cathepsin K / P43235*ENSMUSG0000002811141
Ctsf / Q9R013 / cathepsin F / Q9UBX1*ENSMUSG0000008328235
Ctsh / P49935 / cathepsin H / P09668*ENSMUSG0000003235932
Ctsw / P56203 / cathepsin W / P56202*ENSMUSG0000002491031
CT030254.2 / CTSL* / P07711* / cathepsin L*ENSMUSG0000011490419


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0045930 negative regulation of mitotic cell cycle IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 biological_processGO:0060707 trophoblast giant cell differentiation IMP
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity ISA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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