ENSMUSG00000074871


Mus musculus

Features
Gene ID: ENSMUSG00000074871
  
Biological name :Ctsm
  
Synonyms : cathepsin M / Ctsm
  
Possible biological names infered from orthology : cathepsin L / CTSL / P07711
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B2
Gene start: 61535743
Gene end: 61541839
  
Corresponding Affymetrix probe sets: 10409943 (MoGene1.0st)   10412454 (MoGene1.0st)   1450175_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152912
Ensembl peptide - ENSMUSP00000153564
Ensembl peptide - ENSMUSP00000153101
Ensembl peptide - ENSMUSP00000097050
NCBI entrez gene - 64139     See in Manteia.
MGI - MGI:1927229
RefSeq - XM_011244547
RefSeq - XM_006517309
RefSeq - XM_006517311
RefSeq - XM_006517312
RefSeq - XM_006517313
RefSeq - NM_022326
RefSeq Peptide - NP_071721
swissprot - A0A286YCC4
swissprot - A0A0R4J182
swissprot - A0A286YE81
Ensembl - ENSMUSG00000074871
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctslbENSDARG00000039173Danio rerio
 ctslbENSDARG00000074306Danio rerio
 ctsllENSDARG00000011701Danio rerio
 MGC174155ENSDARG00000095072Danio rerio
 si:dkey-239j18.2ENSDARG00000095254Danio rerio
 si:dkey-239j18.3ENSDARG00000089806Danio rerio
 si:dkey-269i1.4ENSDARG00000095744Danio rerio
 si:dkey-269i1.4ENSDARG00000100833Danio rerio
 si:dkey-26g8.4ENSDARG00000087651Danio rerio
 si:dkey-26g8.5ENSDARG00000089750Danio rerio
 zgc:174153ENSDARG00000079376Danio rerio
 zgc:174154ENSDARG00000075527Danio rerio
 zgc:174855ENSDARG00000094559Danio rerio
 CTSVENSGALG00000012610Gallus gallus
 CTSLENSG00000135047Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cts3 / cathepsin 3 / CTSL* / P07711* / cathepsin L*ENSMUSG0000007487079
Cts8 / Q9JI81 / cathepsin 8 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005744664
Ctsr / Q9JIA9 / cathepsin R / CTSL* / P07711* / cathepsin L*ENSMUSG0000005567964
Cts6 / cathepsin 6 / CTSL* / P07711* / cathepsin L*ENSMUSG0000002144160
Ctsq / cathepsin Q / CTSL* / P07711* / cathepsin L*ENSMUSG0000002143959
Ctsj / Q9R014 / cathepsin J / CTSL* / P07711* / cathepsin L*ENSMUSG0000005529858
Ctsll3 / cathepsin L-like 3 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005672857
Cts7 / Q91ZF2 / cathepsin 7 / CTSL* / P07711* / cathepsin L*ENSMUSG0000002144056
BC051665 / cDNA sequence BC051665 / CTSL* / P07711* / cathepsin L*ENSMUSG0000004224356
Ctsl / P06797 / cathepsin L / CTSV* / O60911* / cathepsin V*ENSMUSG0000002147756
Q80UB0 / 4930486L24Rik / Testin-2 Testin-1 / CTSL* / P07711* / cathepsin L*ENSMUSG0000005034553
Ctsk / P55097 / cathepsin K / P43235*ENSMUSG0000002811144
Ctss / O70370 / cathepsin S / P25774*ENSMUSG0000003864243
Ctsh / P49935 / cathepsin H / P09668*ENSMUSG0000003235934
CT030254.2 / CTSL* / P07711* / cathepsin L*ENSMUSG0000011490433
Ctsf / Q9R013 / cathepsin F / Q9UBX1*ENSMUSG0000008328233
Ctsw / P56203 / cathepsin W / P56202*ENSMUSG0000002491029


Protein motifs (from Interpro)
Interpro ID Name
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr