ENSDARG00000004616


Danio rerio

Features
Gene ID: ENSDARG00000004616
  
Biological name :mtmr2
  
Synonyms : A0JMK5 / mtmr2 / myotubularin related protein 2
  
Possible biological names infered from orthology : Q13614 / Q9Z2D1
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 23608026
Gene end: 23619911
  
Corresponding Affymetrix probe sets: Dr.8133.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000007407
swissprot - A0JMK5
ZFIN ID - ZDB-GENE-990715-14
Ensembl - ENSDARG00000004616
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MTMR2ENSGALG00000017200Gallus gallus
 MTMR2ENSG00000087053Homo sapiens
 Mtmr2ENSMUSG00000031918Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mtmr1a / myotubularin related protein 1a / MTMR1* / Q9Z2C4* / Q13613* / myotubularin related protein 1*ENSDARG0000005669061
mtmr1b / myotubularin related protein 1b / MTMR1* / Q9Z2C4* / Q13613* / myotubularin related protein 1*ENSDARG0000002237859
mtm1 / myotubularin 1 / Q13496*ENSDARG0000003756055
mtmr6 / myotubularin related protein 6 / Q8VE11* / Q9Y217*ENSDARG0000001679433
mtmr8 / Q6TEL0 / myotubularin related protein 8 / Q96EF0*ENSDARG0000000859232
mtmr7a / myotubularin related protein 7a / MTMR7* / Q9Z2C9* / Q9Y216* / myotubularin related protein 7*ENSDARG0000003710131
mtmr7b / myotubularin related protein 7b / MTMR7* / Q9Z2C9* / Q9Y216* / myotubularin related protein 7*ENSDARG0000007041230
mtmr9 / myotubularin related protein 9 / Q96QG7* / Q9Z2D0*ENSDARG0000001586030
zgc:154055ENSDARG0000010392427
sbf2 / SET binding factor 2 / Q86WG5*ENSDARG0000005946027
sbf1 / SET binding factor 1 / O95248* / Q6ZPE2*ENSDARG0000006296826
mtmr3 / myotubularin related protein 3 / Q13615*ENSDARG0000009336418
mtmr3 / myotubularin related protein 3 / Q13615*ENSDARG0000009820115


Protein motifs (from Interpro)
Interpro ID Name
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR004182  GRAM domain
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity ISS
 molecular_functionGO:0004725 protein tyrosine phosphatase activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity ISS


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the ER membrane
Synthesis of PIPs at the early endosome membrane
Synthesis of PIPs at the late endosome membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000062968 sbf1 / SET binding factor 1 / O95248* / Q6ZPE2*  / reaction / complex
 ENSDARG00000059817 mtmr12 / A2BGG1 / myotubularin related protein 12 / Q9C0I1* / Q80TA6* / Mus musculus myotubularin related protein 12 (Mtmr12), transcript variant 2, mRNA.*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr