ENSDARG00000062968


Danio rerio

Features
Gene ID: ENSDARG00000062968
  
Biological name :sbf1
  
Synonyms : sbf1 / SET binding factor 1
  
Possible biological names infered from orthology : O95248 / Q6ZPE2
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 9911043
Gene end: 10002050
  
Corresponding Affymetrix probe sets: Dr.22724.1.A1_at (Zebrafish Array)   NM_001045158_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000086032
Ensembl peptide - ENSDARP00000099695
Ensembl peptide - ENSDARP00000132256
NCBI entrez gene - 568277     See in Manteia.
RefSeq - NM_001045158
RefSeq Peptide - NP_001038623
swissprot - F1QFF3
swissprot - A0A0R4IGU8
swissprot - Q1LXZ0
ZFIN ID - ZDB-GENE-040718-139
Ensembl - ENSDARG00000062968
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SBF1ENSGALG00000043178Gallus gallus
 SBF1ENSG00000100241Homo sapiens
 Sbf1ENSMUSG00000036529Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sbf2 / SET binding factor 2 / Q86WG5*ENSDARG0000005946059
mtmr1a / myotubularin related protein 1a / MTMR1* / Q9Z2C4* / Q13613* / myotubularin related protein 1*ENSDARG0000005669010
mtmr6 / myotubularin related protein 6 / Q8VE11* / Q9Y217*ENSDARG000000167949
mtmr2 / A0JMK5 / myotubularin related protein 2 / Q13614* / Q9Z2D1*ENSDARG000000046169
mtm1 / myotubularin 1 / Q13496*ENSDARG000000375609
mtmr7a / myotubularin related protein 7a / MTMR7* / Q9Z2C9* / Q9Y216* / myotubularin related protein 7*ENSDARG000000371019
zgc:154055ENSDARG000001039248
mtmr7b / myotubularin related protein 7b / MTMR7* / Q9Z2C9* / Q9Y216* / myotubularin related protein 7*ENSDARG000000704128
mtmr9 / myotubularin related protein 9 / Q96QG7* / Q9Z2D0*ENSDARG000000158608
mtmr8 / Q6TEL0 / myotubularin related protein 8 / Q96EF0*ENSDARG000000085928
mtmr1b / myotubularin related protein 1b / MTMR1* / Q9Z2C4* / Q13613* / myotubularin related protein 1*ENSDARG000000223788
mtmr3 / myotubularin related protein 3 / Q13615*ENSDARG000000933645
mtmr3 / myotubularin related protein 3 / Q13615*ENSDARG000000982014


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR001849  Pleckstrin homology domain
 IPR004182  GRAM domain
 IPR005112  dDENN domain
 IPR005113  uDENN domain
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR022096  SBF1/SBF2 domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR030567  Myotubularin-related protein 13


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043087 regulation of GTPase activity IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0019208 phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the ER membrane
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004616 mtmr2 / A0JMK5 / myotubularin related protein 2 / Q13614* / Q9Z2D1*  / reaction / complex
 ENSDARG00000100752 RAB21 / zgc:154045 / P35282* / Q9UL25* / RAB21, member RAS oncogene family*  / reaction
 ENSDARG00000056122 gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *  / reaction






 

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