ENSDARG00000004964


Danio rerio

Features
Gene ID: ENSDARG00000004964
  
Biological name :cyp4t8
  
Synonyms : cyp4t8 / cytochrome P450, family 4, subfamily T, polypeptide 8
  
Possible biological names infered from orthology : Cyp4a10 / CYP4A11 / Cyp4a12a / Cyp4a12b / Cyp4a14 / CYP4A22 / Cyp4a29 / Cyp4a30b / Cyp4a31 / Cyp4a32 / CYP4B1 / CYP4X1 / CYP4Z1 / Cytochrome P450 4A10 / Cytochrome P450 4A12A / Cytochrome P450 4A14 / Cytochrome P450 4B1 / Cytochrome P450 4X1 / cytochrome P450 family 4 subfamily A member 11 / cytochrome P450 family 4 subfamily A member 22 / cytochrome P450, family 4, subfamily a, polypeptide 12B / cytochrome P450, family 4, subfamily a, polypeptide 29 / cytochrome P450, family 4, subfamily a, polypeptide 30b / cytochrome P450, family 4, subfamily a, polypeptide 31 / cytochrome P450, family 4, subfamily a, polypeptide 32 / cytochrome P450 family 4 subfamily B member 1 / cytochrome P450 family 4 subfamily X member 1 / cytochrome P450 family 4 subfamily Z member 1 / O35728 / O88833 / P13584 / Q02928 / Q5TCH4 / Q64462 / Q6A152 / Q86W10 / Q8N118 / Q91WL5
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 4615661
Gene end: 4640578
  
Corresponding Affymetrix probe sets: Dr.15192.1.A1_at (Zebrafish Array)   DrAffx.2.63.S1_at (Zebrafish Array)   DrAffx.2.72.S1_at (Zebrafish Array)   NM_199216_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000071423
Ensembl peptide - ENSDARP00000122081
NCBI entrez gene - 387527     See in Manteia.
RefSeq - XM_005157851
RefSeq - NM_199216
RefSeq Peptide - NP_954686
swissprot - F1QSM0
swissprot - E7FB64
ZFIN ID - ZDB-GENE-031219-3
Ensembl - ENSDARG00000004964
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP4A22ENSGALG00000020688Gallus gallus
 CYP4B7ENSGALG00000010469Gallus gallus
 CYP4B1ENSG00000142973Homo sapiens
 CYP4X1ENSG00000186377Homo sapiens
 CYP4Z1ENSG00000186160Homo sapiens
 Q02928ENSG00000187048Homo sapiens
 Q5TCH4ENSG00000162365Homo sapiens
 Cyp4a12bENSMUSG00000078597Mus musculus
 Cyp4a29ENSMUSG00000083138Mus musculus
 Cyp4a30bENSMUSG00000084346Mus musculus
 Cyp4a31ENSMUSG00000028712Mus musculus
 Cyp4a32ENSMUSG00000063929Mus musculus
 Cyp4b1ENSMUSG00000028713Mus musculus
 Cyp4x1ENSMUSG00000047155Mus musculus
 O35728ENSMUSG00000028715Mus musculus
 O88833ENSMUSG00000066072Mus musculus
 Q91WL5ENSMUSG00000066071Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp4v8 / cytochrome P450, family 4, subfamily V, polypeptide 8 / CYP4V2* / Cyp4v3* / Q6ZWL3* / Q9DBW0* / Cytochrome P450 4V2 * / cytochrome P450 family 4 subfamily V member 2*ENSDARG0000006213232
cyp4v7 / cytochrome P450, family 4, subfamily V, polypeptide 7 / CYP4V2* / Cyp4v3* / Q6ZWL3* / Q9DBW0* / Cytochrome P450 4V2 * / cytochrome P450 family 4 subfamily V member 2*ENSDARG0000006158531
cyp4f3 / cytochrome P450, family 4, subfamily F, polypeptide 3 / Q9HCS2* / Q9HBI6* / Q6NT55* / Q08477* / P78329* / P98187* / CYP4F2* / CYP4F8* / CYP4F11* / CYP4F12* / CYP4F22* / cytochrome ...ENSDARG0000005353024


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Miscellaneous substrates
Eicosanoids
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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