ENSG00000142973


Homo sapiens

Features
Gene ID: ENSG00000142973
  
Biological name :CYP4B1
  
Synonyms : CYP4B1 / cytochrome P450 family 4 subfamily B member 1 / P13584
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p33
Gene start: 46757838
Gene end: 46819413
  
Corresponding Affymetrix probe sets: 1555497_a_at (Human Genome U133 Plus 2.0 Array)   210096_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443212
Ensembl peptide - ENSP00000438995
Ensembl peptide - ENSP00000484629
Ensembl peptide - ENSP00000492115
Ensembl peptide - ENSP00000271153
Ensembl peptide - ENSP00000360987
Ensembl peptide - ENSP00000360991
Ensembl peptide - ENSP00000433068
Ensembl peptide - ENSP00000433367
NCBI entrez gene - 1580     See in Manteia.
OMIM - 124075
RefSeq - XM_017000466
RefSeq - NM_000779
RefSeq - NM_001099772
RefSeq - NM_001319161
RefSeq - NM_001319162
RefSeq - NM_001319163
RefSeq - XM_011540832
RefSeq - XM_011540833
RefSeq Peptide - NP_001306090
RefSeq Peptide - NP_001306092
RefSeq Peptide - NP_001306091
RefSeq Peptide - NP_000770
RefSeq Peptide - NP_001093242
swissprot - Q8IZB0
swissprot - E9PL36
swissprot - Q8WWV1
swissprot - E9PML0
swissprot - F5H1Q8
swissprot - F5H5Q6
swissprot - P13584
Ensembl - ENSG00000142973
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp4t8ENSDARG00000004964Danio rerio
 CYP4A22ENSGALG00000020688Gallus gallus
 CYP4B7ENSGALG00000010469Gallus gallus
 Cyp4b1ENSMUSG00000028713Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q02928 / CYP4A11 / cytochrome P450 family 4 subfamily A member 11ENSG0000018704852
Q5TCH4 / CYP4A22 / cytochrome P450 family 4 subfamily A member 22ENSG0000016236550
CYP4X1 / Q8N118 / cytochrome P450 family 4 subfamily X member 1ENSG0000018637746
CYP4Z1 / Q86W10 / cytochrome P450 family 4 subfamily Z member 1ENSG0000018616044
CYP4F3 / Q08477 / cytochrome P450 family 4 subfamily F member 3ENSG0000018652943
Q9HBI6 / CYP4F11 / cytochrome P450 family 4 subfamily F member 11ENSG0000017190342
CYP4F2 / P78329 / cytochrome P450 family 4 subfamily F member 2ENSG0000018611542
Q6NT55 / CYP4F22 / cytochrome P450 family 4 subfamily F member 22ENSG0000017195441
CYP4F8 / P98187 / cytochrome P450 family 4 subfamily F member 8ENSG0000018652641
Q9HCS2 / CYP4F12 / cytochrome P450 family 4 subfamily F member 12ENSG0000018620440
CYP4V2 / Q6ZWL3 / cytochrome P450 family 4 subfamily V member 2ENSG0000014547632


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006725 cellular aromatic compound metabolic process IEA
 biological_processGO:0018879 biphenyl metabolic process IEA
 biological_processGO:0018917 fluorene metabolic process IEA
 biological_processGO:0042738 exogenous drug catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0015643 toxic substance binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0018585 fluorene oxygenase activity IEA
 molecular_functionGO:0019825 oxygen binding TAS
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Miscellaneous substrates
Eicosanoids
Synthesis of Leukotrienes (LT) and Eoxins (EX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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