ENSG00000186526


Homo sapiens

Features
Gene ID: ENSG00000186526
  
Biological name :CYP4F8
  
Synonyms : CYP4F8 / cytochrome P450 family 4 subfamily F member 8 / P98187
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.12
Gene start: 15615218
Gene end: 15630638
  
Corresponding Affymetrix probe sets: 210576_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477567
Ensembl peptide - ENSP00000482692
Ensembl peptide - ENSP00000479430
Ensembl peptide - ENSP00000478555
NCBI entrez gene - 11283     See in Manteia.
OMIM - 611545
RefSeq - XM_017026232
RefSeq - NM_007253
RefSeq Peptide - NP_009184
swissprot - A0A087WVG9
swissprot - A0A087WZJ1
swissprot - P98187
swissprot - A0A087WUC9
Ensembl - ENSG00000186526
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp4f3ENSDARG00000053530Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP4F2 / P78329 / cytochrome P450 family 4 subfamily F member 2ENSG0000018611581
Q9HBI6 / CYP4F11 / cytochrome P450 family 4 subfamily F member 11ENSG0000017190379
Q9HCS2 / CYP4F12 / cytochrome P450 family 4 subfamily F member 12ENSG0000018620478
CYP4F3 / Q08477 / cytochrome P450 family 4 subfamily F member 3ENSG0000018652977
Q6NT55 / CYP4F22 / cytochrome P450 family 4 subfamily F member 22ENSG0000017195460
Q02928 / CYP4A11 / cytochrome P450 family 4 subfamily A member 11ENSG0000018704844
Q5TCH4 / CYP4A22 / cytochrome P450 family 4 subfamily A member 22ENSG0000016236542
CYP4B1 / P13584 / cytochrome P450 family 4 subfamily B member 1ENSG0000014297341
CYP4X1 / Q8N118 / cytochrome P450 family 4 subfamily X member 1ENSG0000018637738
CYP4Z1 / Q86W10 / cytochrome P450 family 4 subfamily Z member 1ENSG0000018616037
CYP4V2 / Q6ZWL3 / cytochrome P450 family 4 subfamily V member 2ENSG0000014547633


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006690 icosanoid metabolic process TAS
 biological_processGO:0006693 prostaglandin metabolic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0018685 alkane 1-monooxygenase activity TAS
 molecular_functionGO:0019825 oxygen binding TAS
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Eicosanoids
Synthesis of Leukotrienes (LT) and Eoxins (EX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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