ENSG00000186204


Homo sapiens

Features
Gene ID: ENSG00000186204
  
Biological name :CYP4F12
  
Synonyms : CYP4F12 / cytochrome P450 family 4 subfamily F member 12 / Q9HCS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.12
Gene start: 15672757
Gene end: 15697174
  
Corresponding Affymetrix probe sets: 206539_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448998
Ensembl peptide - ENSP00000448560
Ensembl peptide - ENSP00000449703
Ensembl peptide - ENSP00000321821
Ensembl peptide - ENSP00000430849
Ensembl peptide - ENSP00000446812
Ensembl peptide - ENSP00000447922
NCBI entrez gene - 66002     See in Manteia.
OMIM - 611485
RefSeq - XM_017027172
RefSeq - XM_011528202
RefSeq - XM_011528203
RefSeq - XM_011528204
RefSeq - XM_011528205
RefSeq - XM_011528207
RefSeq - XM_011528208
RefSeq - NM_023944
RefSeq - XM_006722850
RefSeq Peptide - NP_076433
swissprot - F8VR75
swissprot - F8VU50
swissprot - F8VZP1
swissprot - A0A0A0MR49
swissprot - Q9HCS2
Ensembl - ENSG00000186204
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp4f3ENSDARG00000053530Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HBI6 / CYP4F11 / cytochrome P450 family 4 subfamily F member 11ENSG0000017190383
CYP4F2 / P78329 / cytochrome P450 family 4 subfamily F member 2ENSG0000018611581
CYP4F3 / Q08477 / cytochrome P450 family 4 subfamily F member 3ENSG0000018652978
CYP4F8 / P98187 / cytochrome P450 family 4 subfamily F member 8ENSG0000018652677
Q6NT55 / CYP4F22 / cytochrome P450 family 4 subfamily F member 22ENSG0000017195462
Q02928 / CYP4A11 / cytochrome P450 family 4 subfamily A member 11ENSG0000018704843
Q5TCH4 / CYP4A22 / cytochrome P450 family 4 subfamily A member 22ENSG0000016236542
CYP4B1 / P13584 / cytochrome P450 family 4 subfamily B member 1ENSG0000014297339
CYP4X1 / Q8N118 / cytochrome P450 family 4 subfamily X member 1ENSG0000018637738
CYP4Z1 / Q86W10 / cytochrome P450 family 4 subfamily Z member 1ENSG0000018616036
CYP4V2 / Q6ZWL3 / cytochrome P450 family 4 subfamily V member 2ENSG0000014547632


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process ISS
 biological_processGO:0001676 long-chain fatty acid metabolic process ISS
 biological_processGO:0003091 renal water homeostasis ISS
 biological_processGO:0003095 pressure natriuresis ISS
 biological_processGO:0017144 drug metabolic process ISS
 biological_processGO:0019369 arachidonic acid metabolic process ISS
 biological_processGO:0019373 epoxygenase P450 pathway ISS
 biological_processGO:0036101 leukotriene B4 catabolic process ISS
 biological_processGO:0042360 vitamin E metabolic process ISS
 biological_processGO:0055078 sodium ion homeostasis ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISS
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity ISS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0018685 alkane 1-monooxygenase activity ISS
 molecular_functionGO:0019825 oxygen binding TAS
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050051 leukotriene-B4 20-monooxygenase activity ISS
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Eicosanoids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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