ENSDARG00000006283


Danio rerio

Features
Gene ID: ENSDARG00000006283
  
Biological name :waslb
  
Synonyms : waslb / Wiskott-Aldrich syndrome-like b
  
Possible biological names infered from orthology : O00401 / Q91YD9 / WASL / Wiskott-Aldrich syndrome like / Wiskott-Aldrich syndrome-like (human)
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 4079418
Gene end: 4111767
  
Corresponding Affymetrix probe sets: Dr.10901.1.S1_at (Zebrafish Array)   NM_201059_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000005823
NCBI entrez gene - 394034     See in Manteia.
RefSeq - NM_201059
RefSeq Peptide - NP_957353
swissprot - Q5RGR6
ZFIN ID - ZDB-GENE-040426-718
Ensembl - ENSDARG00000006283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000037819Gallus gallus
 WASLENSGALG00000008797Gallus gallus
 WASLENSG00000106299Homo sapiens
 WaslENSMUSG00000029684Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wasla / Wiskott-Aldrich syndrome-like a / WASL* / Q91YD9* / O00401* / Wiskott-Aldrich syndrome like* / Wiskott-Aldrich syndrome-like (human)*ENSDARG0000001411370
wasb / Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b / WAS* / P70315* / P42768* / Wiskott-Aldrich syndrome*ENSDARG0000002635041
wasa / Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a / WAS* / P70315* / P42768* / Wiskott-Aldrich syndrome*ENSDARG0000001514938
si:dkey-197j19.6ENSDARG0000009062816


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000697  WH1/EVH1 domain
 IPR003124  WH2 domain
 IPR011026  Wiscott-Aldrich syndrome protein, C-terminal
 IPR011993  PH-like domain superfamily
 IPR030214  Neural Wiskott-Aldrich syndrome protein
 IPR033927  WASP family, EVH1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030099 myeloid cell differentiation IMP
 biological_processGO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
NOSTRIN mediated eNOS trafficking
Nephrin family interactions
EPHB-mediated forward signaling
DCC mediated attractive signaling
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000094 blood island blood island has fewer parts of type hematopoietic stem cell , abnormal
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 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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