ENSDARG00000006356


Danio rerio

Features
Gene ID: ENSDARG00000006356
  
Biological name :slc18a3a
  
Synonyms : Q08C75 / slc18a3a / solute carrier family 18 (vesicular acetylcholine transporter), member 3a
  
Possible biological names infered from orthology : Q16572 / SLC18A3 / solute carrier family 18 member A3
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 29422049
Gene end: 29424454
  
Corresponding Affymetrix probe sets: Dr.12928.1.A1_at (Zebrafish Array)   NM_001077550_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000012428
NCBI entrez gene - 559347     See in Manteia.
RefSeq - NM_001077550
RefSeq Peptide - NP_001071018
swissprot - B2GS60
swissprot - Q08C75
ZFIN ID - ZDB-GENE-060929-990
Ensembl - ENSDARG00000006356
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC18A3ENSGALG00000041103Gallus gallus
 Q16572ENSG00000187714Homo sapiens
 Slc18a3ENSMUSG00000100241Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CABZ01112647.1 / Q16572* / SLC18A3* / solute carrier family 18 member A3*ENSDARG0000010752764
slc18a2 / solute carrier family 18 (vesicular monoamine transporter), member 2ENSDARG0000001511037
BX088696.1 / P54219* / SLC18A1* / solute carrier family 18 member A1*ENSDARG0000007815734
slc18b1 / solute carrier family 18, subfamily B, member 1 / Q6NT16* / D3Z5L6* / solute carrier family 18 member B1* / Mus musculus solute carrier family 18, subfamily B, member 1 (Slc18b1),...ENSDARG0000004404718


Protein motifs (from Interpro)
Interpro ID Name
 IPR004734  Multidrug resistance protein
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006855 drug transmembrane transport IEA
 biological_processGO:0015695 organic cation transport IEA
 biological_processGO:0015893 drug transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0072488 ammonium transmembrane transport IEA
 biological_processGO:1901374 acetate ester transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030121 AP-1 adaptor complex IBA
 cellular_componentGO:0030122 AP-2 adaptor complex IBA
 molecular_functionGO:0005277 acetylcholine transmembrane transporter activity IBA
 molecular_functionGO:0015238 drug transmembrane transporter activity IEA
 molecular_functionGO:0042166 acetylcholine binding IBA


Pathways (from Reactome)
Pathway description
Acetylcholine Neurotransmitter Release Cycle
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042350 syt1b / synaptotagmin Ib / SYT1* / P46096* / P21579* / synaptotagmin 1* / synaptotagmin I*  / complex / reaction
 ENSDARG00000056347 rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*  / complex / reaction
 ENSDARG00000043835 rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*  / reaction / complex
 ENSDARG00000006356 Q08C75 / slc18a3a / solute carrier family 18 (vesicular acetylcholine transporter), member 3a / Q16572* / SLC18A3* / solute carrier family 18 member A3*  / reaction
 ENSDARG00000030614 syt1a / synaptotagmin Ia / SYT1* / P46096* / P21579* / synaptotagmin 1* / synaptotagmin I*  / reaction / complex






 

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