ENSDARG00000030614


Danio rerio

Features
Gene ID: ENSDARG00000030614
  
Biological name :syt1a
  
Synonyms : synaptotagmin Ia / syt1a
  
Possible biological names infered from orthology : P21579 / P46096 / synaptotagmin 1 / synaptotagmin I / SYT1
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 21129752
Gene end: 21315399
  
Corresponding Affymetrix probe sets: Dr.11127.1.A1_at (Zebrafish Array)   Dr.11127.2.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000041860
Ensembl peptide - ENSDARP00000141860
NCBI entrez gene - 436736     See in Manteia.
RefSeq - XM_005164872
RefSeq - NM_001327829
RefSeq - XM_009300373
RefSeq - XM_017354995
RefSeq - XM_017354996
RefSeq - XM_005164874
RefSeq Peptide - NP_001314758
swissprot - Q5TZ27
ZFIN ID - ZDB-GENE-040718-165
Ensembl - ENSDARG00000030614
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SYT1ENSGALG00000041094Gallus gallus
 SYT1ENSG00000067715Homo sapiens
 Syt1ENSMUSG00000035864Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
syt2a / synaptotagmin IIa / SYT2* / Q8N9I0* / synaptotagmin 2* / synaptotagmin II*ENSDARG0000002520668
syt1b / synaptotagmin Ib / SYT1* / P46096* / P21579* / synaptotagmin 1* / synaptotagmin I*ENSDARG0000004235063
syt5b / synaptotagmin Vb / SYT5* / O00445* / Q9R0N5* / synaptotagmin 5*ENSDARG0000001164059
syt5a / synaptotagmin Va / SYT5* / O00445* / Q9R0N5* / synaptotagmin 5*ENSDARG0000003794158
syt6a / synaptotagmin VIa / SYT6* / Q9R0N8* / Q5T7P8* / synaptotagmin 6* / synaptotagmin VI*ENSDARG0000007673037
syt3 / synaptotagmin III / Q9BQG1* / synaptotagmin 3*ENSDARG0000007583036
syt6b / synaptotagmin VIb / SYT6* / Q9R0N8* / Q5T7P8* / synaptotagmin 6* / synaptotagmin VI*ENSDARG0000003146336
syt10 / synaptotagmin X / Q6XYQ8* / Q9R0N4* / synaptotagmin 10*ENSDARG0000004575036
syt9a / synaptotagmin IXa / SYT9* / Q86SS6* / synaptotagmin 9*ENSDARG0000000399435
syt9b / synaptotagmin IXb / SYT9* / Q86SS6* / Q9R0N9* / synaptotagmin 9*ENSDARG0000002923935
SYT2 / synaptotagmin 2 / Q8N9I0*ENSDARG0000001416935
syt7b / synaptotagmin VIIb / SYT7* / O43581* / Q9R0N7* / synaptotagmin 7*ENSDARG0000007806034
syt11a / synaptotagmin XIa / SYT11* / Q9BT88* / Q9R0N3* / synaptotagmin 11*ENSDARG0000005791333
syt7a / synaptotagmin VIIa / SYT7* / O43581* / Q9R0N7* / synaptotagmin 7*ENSDARG0000006356833
syt11b / synaptotagmin XIb / SYT11* / Q9BT88* / Q9R0N3* / synaptotagmin 11*ENSDARG0000005610531
syt4 / synaptotagmin IV / P40749* / Q9H2B2* / synaptotagmin 4*ENSDARG0000003650529


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR015428  Synaptotagmin 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IBA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006356 Q08C75 / slc18a3a / solute carrier family 18 (vesicular acetylcholine transporter), member 3a / Q16572* / SLC18A3* / solute carrier family 18 member A3*  / reaction / complex
 ENSDARG00000043835 rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*  / complex
 ENSDARG00000030614 syt1a / synaptotagmin Ia / SYT1* / P46096* / P21579* / synaptotagmin 1* / synaptotagmin I*  / complex
 ENSDARG00000056347 rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*  / complex
 ENSDARG00000042350 syt1b / synaptotagmin Ib / SYT1* / P46096* / P21579* / synaptotagmin 1* / synaptotagmin I*  / complex
 ENSDARG00000016480 slc17a7a / solute carrier family 17 (vesicular glutamate transporter), member 7a / Q9P2U7* / Q3TXX4* / SLC17A7* / solute carrier family 17 member 7* / Vesicular glutamate transporter 1 *  / complex
 ENSDARG00000090106 slc17a7b / solute carrier family 17 (vesicular glutamate transporter), member 7b / Q9P2U7* / Q3TXX4* / SLC17A7* / solute carrier family 17 member 7* / Vesicular glutamate transporter 1 *  / complex






 

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