ENSGALG00000041094


Gallus gallus

Features
Gene ID: ENSGALG00000041094
  
Biological name :SYT1
  
Synonyms : P47191 / Synaptotagmin-1 / SYT1
  
Possible biological names infered from orthology : P21579 / P46096 / synaptotagmin I
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 39230582
Gene end: 39452545
  
Corresponding Affymetrix probe sets: Gga.643.1.S1_at (Chicken Array)   Gga.643.1.S1_s_at (Chicken Array)   GgaAffx.21698.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056597
NCBI entrez gene - 396083     See in Manteia.
RefSeq - XM_015278895
RefSeq - NM_205171
RefSeq - XM_015278775
RefSeq - XM_015278844
RefSeq - XM_015278687
RefSeq - XM_015278728
RefSeq Peptide - NP_990502
swissprot - P47191
Ensembl - ENSGALG00000041094
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt1aENSDARG00000030614Danio rerio
 syt1bENSDARG00000042350Danio rerio
 SYT1ENSG00000067715Homo sapiens
 Syt1ENSMUSG00000035864Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYT2 / synaptotagmin 2 / Q8N9I0* / synaptotagmin II*ENSGALG0000002603375
SYT8 / synaptotagmin 8 / Q8NBV8* / Q9R0N6* / synaptotagmin VIII*ENSGALG0000000660248
SYT10 / synaptotagmin 10 / Q6XYQ8* / Q9R0N4* / synaptotagmin X*ENSGALG0000001291137
SYT9 / synaptotagmin 9 / Q86SS6* / Q9R0N9*ENSGALG0000000526536
SYT6 / synaptotagmin 6 / Q5T7P8* / Q9R0N8* / synaptotagmin VI*ENSGALG0000000196836
SYT7 / synaptotagmin 7 / O43581* / Q9R0N7*ENSGALG0000004313933
SYT11 / synaptotagmin 11 / Q9BT88* / Q9R0N3*ENSGALG0000001464630
SYT4 / synaptotagmin 4 / P40749* / Q9H2B2*ENSGALG0000004262629


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR015428  Synaptotagmin 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0014059 regulation of dopamine secretion IEA
 biological_processGO:0016079 synaptic vesicle exocytosis IEA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:0050806 positive regulation of synaptic transmission IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter IEA
 biological_processGO:1903861 positive regulation of dendrite extension IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IBA
 cellular_componentGO:0031045 dense core granule IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042584 chromaffin granule membrane IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IBA
 molecular_functionGO:0017075 syntaxin-1 binding IEA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IEA


Pathways (from Reactome)
Pathway description
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010579 STON2 / stonin 2 / Q8BZ60* / Q8WXE9*  / reaction / complex
 ENSGALG00000041094 SYT1 / P47191 / Synaptotagmin-1 / P46096* / P21579* / synaptotagmin I*  / complex






 

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