ENSDARG00000006900


Danio rerio

Features
Gene ID: ENSDARG00000006900
  
Biological name :impdh2
  
Synonyms : B0UXP9 / impdh2 / IMP (inosine 5-monophosphate) dehydrogenase 2
  
Possible biological names infered from orthology : Inosine-5-monophosphate dehydrogenase 2 / inosine monophosphate dehydrogenase 2 / P12268 / P24547
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 26059677
Gene end: 26079140
  
Corresponding Affymetrix probe sets: Dr.2636.1.S1_at (Zebrafish Array)   NM_201464_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000024354
NCBI entrez gene - 317745     See in Manteia.
RefSeq - NM_201464
RefSeq Peptide - NP_958872
swissprot - B0UXP9
ZFIN ID - ZDB-GENE-030114-5
Ensembl - ENSDARG00000006900
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IMPDH2ENSGALG00000006910Gallus gallus
 IMPDH2ENSG00000178035Homo sapiens
 Impdh2ENSMUSG00000062867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6GMG5 / impdh1a / IMP (inosine 5-monophosphate) dehydrogenase 1a / P50096* / IMPDH1* / P20839* / inosine monophosphate dehydrogenase 1* / Inosine-5-monophosphate dehydrogenase 1 *ENSDARG0000004233683
Q5RGV1 / impdh1b / IMP (inosine 5-monophosphate) dehydrogenase 1b / P50096* / IMPDH1* / P20839* / inosine monophosphate dehydrogenase 1* / Inosine-5-monophosphate dehydrogenase 1 *ENSDARG0000002952482
gmpr2 / guanosine monophosphate reductase 2 / Q99L27* / Q9P2T1*ENSDARG0000006130119
gmpr / guanosine monophosphate reductase / P36959* / Q9DCZ1*ENSDARG0000001616019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000644  CBS domain
 IPR001093  IMP dehydrogenase/GMP reductase
 IPR005990  Inosine-5"-monophosphate dehydrogenase
 IPR013785  Aldolase-type TIM barrel
 IPR015875  IMP dehydrogenase / GMP reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006177 GMP biosynthetic process IEA
 biological_processGO:0006183 GTP biosynthetic process IBA
 biological_processGO:0007623 circadian rhythm IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003938 IMP dehydrogenase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006900 B0UXP9 / impdh2 / IMP (inosine 5-monophosphate) dehydrogenase 2 / P24547* / P12268* / inosine monophosphate dehydrogenase 2* / Inosine-5-monophosphate dehydrogenase 2 *  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr