ENSDARG00000061301


Danio rerio

Features
Gene ID: ENSDARG00000061301
  
Biological name :gmpr2
  
Synonyms : gmpr2 / guanosine monophosphate reductase 2
  
Possible biological names infered from orthology : Q99L27 / Q9P2T1
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 24196575
Gene end: 24204665
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000081732
Ensembl peptide - ENSDARP00000135056
NCBI entrez gene - 678545     See in Manteia.
swissprot - Q1RLT1
ZFIN ID - ZDB-GENE-030131-1238
Ensembl - ENSDARG00000061301
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GMPR2ENSG00000100938Homo sapiens
 Gmpr2ENSMUSG00000002326Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gmpr / guanosine monophosphate reductase / P36959* / Q9DCZ1*ENSDARG0000001616078
Q5RGV1 / impdh1b / IMP (inosine 5-monophosphate) dehydrogenase 1b / P50096* / IMPDH1* / P20839* / inosine monophosphate dehydrogenase 1* / Inosine-5-monophosphate dehydrogenase 1 *ENSDARG0000002952429
B0UXP9 / impdh2 / IMP (inosine 5-monophosphate) dehydrogenase 2 / P24547* / P12268* / inosine monophosphate dehydrogenase 2* / Inosine-5-monophosphate dehydrogenase 2 *ENSDARG0000000690028
Q6GMG5 / impdh1a / IMP (inosine 5-monophosphate) dehydrogenase 1a / P50096* / IMPDH1* / P20839* / inosine monophosphate dehydrogenase 1* / Inosine-5-monophosphate dehydrogenase 1 *ENSDARG0000004233628


Protein motifs (from Interpro)
Interpro ID Name
 IPR001093  IMP dehydrogenase/GMP reductase
 IPR005993  GMP reductase
 IPR013785  Aldolase-type TIM barrel
 IPR015875  IMP dehydrogenase / GMP reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006144 purine nucleobase metabolic process IEA
 biological_processGO:0006163 purine nucleotide metabolic process IEA
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:1902560 GMP reductase complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003920 GMP reductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000061301 gmpr2 / guanosine monophosphate reductase 2 / Q99L27* / Q9P2T1*  / complex






 

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