ENSMUSG00000002326


Mus musculus

Features
Gene ID: ENSMUSG00000002326
  
Biological name :Gmpr2
  
Synonyms : Gmpr2 / guanosine monophosphate reductase 2 / Q99L27
  
Possible biological names infered from orthology : Q9P2T1
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C3
Gene start: 55671941
Gene end: 55679200
  
Corresponding Affymetrix probe sets: 10415363 (MoGene1.0st)   1416356_at (Mouse Genome 430 2.0 Array)   1429180_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000002397
Ensembl peptide - ENSMUSP00000154349
Ensembl peptide - ENSMUSP00000154721
NCBI entrez gene - 105446     See in Manteia.
MGI - MGI:1917903
RefSeq - XM_011244882
RefSeq - NM_177992
RefSeq - XM_006518366
RefSeq Peptide - NP_818773
swissprot - Q99L27
Ensembl - ENSMUSG00000002326
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmpr2ENSDARG00000061301Danio rerio
 GMPR2ENSG00000100938Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gmpr / Q9DCZ1 / guanosine monophosphate reductase / P36959*ENSMUSG0000000025378
Impdh1 / P50096 / Inosine-5-monophosphate dehydrogenase 1 / P20839* / inosine monophosphate dehydrogenase 1*ENSMUSG0000000350029
Impdh2 / P24547 / Inosine-5-monophosphate dehydrogenase 2 / P12268* / inosine monophosphate dehydrogenase 2*ENSMUSG0000006286728


Protein motifs (from Interpro)
Interpro ID Name
 IPR001093  IMP dehydrogenase/GMP reductase
 IPR005993  GMP reductase
 IPR013785  Aldolase-type TIM barrel
 IPR015875  IMP dehydrogenase / GMP reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006144 purine nucleobase metabolic process IEA
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0030224 monocyte differentiation ISO
 biological_processGO:0046037 GMP metabolic process ISS
 biological_processGO:0046038 GMP catabolic process ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:1902560 GMP reductase complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003920 GMP reductase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002326 Gmpr2 / Q99L27 / guanosine monophosphate reductase 2 / Q9P2T1*  / complex






 

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