ENSMUSG00000000253


Mus musculus

Features
Gene ID: ENSMUSG00000000253
  
Biological name :Gmpr
  
Synonyms : Gmpr / guanosine monophosphate reductase / Q9DCZ1
  
Possible biological names infered from orthology : P36959
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 45507444
Gene end: 45553800
  
Corresponding Affymetrix probe sets: 10404885 (MoGene1.0st)   1448530_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000260
Ensembl peptide - ENSMUSP00000120825
NCBI entrez gene - 66355     See in Manteia.
MGI - MGI:1913605
RefSeq - XM_017315562
RefSeq - NM_025508
RefSeq - XM_017315561
RefSeq Peptide - NP_079784
swissprot - Q9DCZ1
swissprot - F6VY18
Ensembl - ENSMUSG00000000253
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmprENSDARG00000016160Danio rerio
 GMPRENSGALG00000012705Gallus gallus
 GMPRENSG00000137198Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gmpr2 / Q99L27 / guanosine monophosphate reductase 2 / Q9P2T1*ENSMUSG0000000232679
Impdh2 / P24547 / Inosine-5-monophosphate dehydrogenase 2 / P12268* / inosine monophosphate dehydrogenase 2*ENSMUSG0000006286728
Impdh1 / P50096 / Inosine-5-monophosphate dehydrogenase 1 / P20839* / inosine monophosphate dehydrogenase 1*ENSMUSG0000000350028


Protein motifs (from Interpro)
Interpro ID Name
 IPR001093  IMP dehydrogenase/GMP reductase
 IPR005993  GMP reductase
 IPR013785  Aldolase-type TIM barrel
 IPR015875  IMP dehydrogenase / GMP reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006144 purine nucleobase metabolic process IEA
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:1902560 GMP reductase complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003920 GMP reductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000253 Gmpr / Q9DCZ1 / guanosine monophosphate reductase / P36959*  / complex






 

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