ENSG00000100938


Homo sapiens

Features
Gene ID: ENSG00000100938
  
Biological name :GMPR2
  
Synonyms : GMPR2 / guanosine monophosphate reductase 2 / Q9P2T1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q12
Gene start: 24232422
Gene end: 24239242
  
Corresponding Affymetrix probe sets: 217990_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454038
Ensembl peptide - ENSP00000454009
Ensembl peptide - ENSP00000454138
Ensembl peptide - ENSP00000480342
Ensembl peptide - ENSP00000334409
Ensembl peptide - ENSP00000347449
Ensembl peptide - ENSP00000382369
Ensembl peptide - ENSP00000392859
Ensembl peptide - ENSP00000405743
Ensembl peptide - ENSP00000452617
Ensembl peptide - ENSP00000452670
Ensembl peptide - ENSP00000452683
Ensembl peptide - ENSP00000452766
Ensembl peptide - ENSP00000452840
Ensembl peptide - ENSP00000453079
Ensembl peptide - ENSP00000453139
Ensembl peptide - ENSP00000453299
Ensembl peptide - ENSP00000453355
Ensembl peptide - ENSP00000453537
Ensembl peptide - ENSP00000453560
Ensembl peptide - ENSP00000453594
Ensembl peptide - ENSP00000453714
Ensembl peptide - ENSP00000453761
Ensembl peptide - ENSP00000453772
Ensembl peptide - ENSP00000453833
Ensembl peptide - ENSP00000453895
NCBI entrez gene - 51292     See in Manteia.
OMIM - 610781
RefSeq - NM_001283023
RefSeq - NM_001002000
RefSeq - NM_001002001
RefSeq - NM_001002002
RefSeq - NM_001283021
RefSeq - NM_001283022
RefSeq - NM_016576
RefSeq - XM_005267740
RefSeq - XM_005267741
RefSeq - XM_005267742
RefSeq - XM_006720165
RefSeq - XM_017021356
RefSeq - XM_017021357
RefSeq - XM_017021358
RefSeq - XM_017021359
RefSeq - XM_017021360
RefSeq Peptide - NP_001269952
RefSeq Peptide - NP_057660
RefSeq Peptide - NP_001002002
RefSeq Peptide - NP_001269950
RefSeq Peptide - NP_001002000
RefSeq Peptide - NP_001002001
RefSeq Peptide - NP_001269951
swissprot - F8WAN9
swissprot - H0YK13
swissprot - H0YK71
swissprot - H0YKE1
swissprot - H0YKK3
swissprot - H0YL68
swissprot - H0YLB8
swissprot - H0YLV5
swissprot - H0YMB3
swissprot - H0YMG3
swissprot - H0YMR9
swissprot - H0YMV5
swissprot - H0YMW6
swissprot - H0YN74
swissprot - H0YN22
swissprot - H0YNH0
swissprot - H0YNJ6
swissprot - H0YNS9
swissprot - A0A087WWM4
swissprot - Q9P2T1
swissprot - A0A0B4J281
Ensembl - ENSG00000100938
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmpr2ENSDARG00000061301Danio rerio
 Gmpr2ENSMUSG00000002326Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GMPR / P36959 / guanosine monophosphate reductaseENSG0000013719864
IMPDH1 / P20839 / inosine monophosphate dehydrogenase 1ENSG0000010634825
IMPDH2 / P12268 / inosine monophosphate dehydrogenase 2ENSG0000017803524


Protein motifs (from Interpro)
Interpro ID Name
 IPR001093  IMP dehydrogenase/GMP reductase
 IPR005990  Inosine-5"-monophosphate dehydrogenase
 IPR005993  GMP reductase
 IPR013785  Aldolase-type TIM barrel
 IPR015875  IMP dehydrogenase / GMP reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006144 purine nucleobase metabolic process IEA
 biological_processGO:0006163 purine nucleotide metabolic process IEA
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0043101 purine-containing compound salvage TAS
 biological_processGO:0046037 GMP metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:1902560 GMP reductase complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003920 GMP reductase activity IEA
 molecular_functionGO:0003938 IMP dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100938 GMPR2 / Q9P2T1 / guanosine monophosphate reductase 2  / complex






 

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