ENSDARG00000006911


Danio rerio

Features
Gene ID: ENSDARG00000006911
  
Biological name :wnt8b
  
Synonyms : wingless-type MMTV integration site family, member 8b / wnt8b
  
Possible biological names infered from orthology : Q93098 / Wnt family member 8B
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 29991090
Gene end: 30006260
  
Corresponding Affymetrix probe sets: Dr.623.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000049623
swissprot - B7ZD55
ZFIN ID - ZDB-GENE-990415-279
Ensembl - ENSDARG00000006911
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNT8BENSGALG00000005733Gallus gallus
 WNT8BENSG00000075290Homo sapiens
 Wnt8bENSMUSG00000036961Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnt8a / wingless-type MMTV integration site family, member 8a / Q64527* / Q9H1J5* / Wnt family member 8A*ENSDARG0000005291065
wnt8a / wingless-type MMTV integration site family, member 8a / Q64527* / Q9H1J5* / Wnt family member 8A*ENSDARG0000007850762
wnt10a / wingless-type MMTV integration site family, member 10a / Q9GZT5* / Wnt family member 10A*ENSDARG0000001715535
wnt10b / wingless-type MMTV integration site family, member 10b / O00744* / P48614* / Wnt family member 10B*ENSDARG0000004092531
wnt9b / wingless-type MMTV integration site family, member 9B / O14905* / O35468* / Wnt family member 9B*ENSDARG0000003788931
wnt9a / wingless-type MMTV integration site family, member 9A / O14904* / Wnt family member 9A*ENSDARG0000006343730


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR013301  Wnt-8 protein
 IPR018161  Wnt protein, conserved site
 IPR034311  Protein Wnt-8B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005102 signaling receptor binding IEA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain disorganized , abnormal
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 ZFA:0000032 hypothalamus hypothalamus posterior side morphology , abnormal
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 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
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 ZFA:0000059 postoptic commissure postoptic commissure decreased size , abnormal
postoptic commissure has fewer parts of type postoptic commissure axon, abnormal
postoptic commissure medial region has fewer parts of type glial cell (sensu Vertebrata) , abnormal
postoptic commissure commissural neuron axon guidance decreased process quality , abnormal
postoptic commissure axon defasciculated , abnormal
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 ZFA:0000101 diencephalon diencephalon dopaminergic neuron increased amount , abnormal
diencephalon dopaminergic neuron decreased amount , abnormal
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 ZFA:0000109 forebrain forebrain lacks all parts of type anterior commissure , abnormal
forebrain Roundabout signaling pathway involved in axon guidance increased process quality , abnormal
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 ZFA:0000445 optic tectum optic tectum hypoplastic , abnormal
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 ZFA:0001064 rhombomere rhombomere primary neuron crowded , abnormal
rhombomere primary neuron disorganized , abnormal
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 ZFA:0001108 anterior commissure anterior commissure has fewer parts of type anterior commissure axon, abnormal
anterior commissure medial region has fewer parts of type glial cell (sensu Vertebrata) , abnormal
anterior commissure commissural neuron axon guidance decreased process quality , abnormal
anterior commissure lacks all parts of type anterior commissure axon, abnormal
anterior commissure medial region lacks all parts of type glial cell (sensu Vertebrata) , abnormal
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 ZFA:0001692 hindbrain commissure hindbrain commissure neuron absent , abnormal
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 ZFA:0009292 radial glial cell radial glial cell cell projection irregular spatial pattern , abnormal
radial glial cell cell projection tangled , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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