ENSMUSG00000036961


Mus musculus

Features
Gene ID: ENSMUSG00000036961
  
Biological name :Wnt8b
  
Synonyms : wingless-type MMTV integration site family, member 8B / Wnt8b
  
Possible biological names infered from orthology : Q93098 / Wnt family member 8B
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 44493472
Gene end: 44514273
  
Corresponding Affymetrix probe sets: 10463371 (MoGene1.0st)   1421439_at (Mouse Genome 430 2.0 Array)   1421440_at (Mouse Genome 430 2.0 Array)   1441316_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042867
NCBI entrez gene - 22423     See in Manteia.
MGI - MGI:109485
RefSeq - NM_011720
RefSeq Peptide - NP_035850
swissprot - Q8BQD1
Ensembl - ENSMUSG00000036961
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt8bENSDARG00000006911Danio rerio
 WNT8BENSGALG00000005733Gallus gallus
 WNT8BENSG00000075290Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wnt8a / Q64527 / wingless-type MMTV integration site family, member 8A / Q9H1J5* / Wnt family member 8A*ENSMUSG0000001228255
P70701 / Wnt10a / wingless-type MMTV integration site family, member 10A / Q9GZT5* / Wnt family member 10A*ENSMUSG0000002616734
P48614 / Wnt10b / wingless-type MMTV integration site family, member 10B / O00744* / Wnt family member 10B*ENSMUSG0000002299632
Wnt9b / O35468 / wingless-type MMTV integration site family, member 9B / O14905* / Wnt family member 9B*ENSMUSG0000001848632
Wnt9a / Q8R5M2 / wingless-type MMTV integration site family, member 9A / O14904* / Wnt family member 9A*ENSMUSG0000000012632


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR013301  Wnt-8 protein
 IPR018161  Wnt protein, conserved site
 IPR034311  Protein Wnt-8B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0048018 receptor ligand activity IEA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003233 Dvl3 / Q61062 / Segment polarity DVL-3 / Q92997* / dishevelled segment polarity protein 3*  / complex
 ENSMUSG00000020888 Dvl2 / Q60838 / Segment polarity DVL-2 / O14641* / dishevelled segment polarity protein 2*  / complex
 ENSMUSG00000050288 Fzd2 / Q9JIP6 / Frizzled-2 / Q14332* / frizzled class receptor 2*  / complex
 ENSMUSG00000030201 Lrp6 / LDL receptor related protein 6 / O75581*  / complex
 ENSMUSG00000022812 Gsk3b / Q9WV60 / glycogen synthase kinase 3 beta / P49841*  / reaction / complex
 ENSMUSG00000044674 Fzd1 / O70421 / Frizzled-1 / Q9UP38* / frizzled class receptor 1*  / complex
 ENSMUSG00000024182 Axin1 / O15169*  / reaction / complex
 ENSMUSG00000029071 Dvl1 / P51141 / Segment polarity DVL-1 / O14640* / dishevelled segment polarity protein 1*  / complex






 

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