ENSDARG00000007988


Danio rerio

Features
Gene ID: ENSDARG00000007988
  
Biological name :masp2
  
Synonyms : mannan-binding lectin serine peptidase 2 / masp2
  
Possible biological names infered from orthology : Mannan-binding lectin serine protease 2 Mannan-binding lectin serine protease 2 A chain Mannan-binding lectin serine protease 2 B chain / O00187 / Q91WP0
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 28770225
Gene end: 28796157
  
Corresponding Affymetrix probe sets: Dr.17391.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000116209
Ensembl peptide - ENSDARP00000122507
NCBI entrez gene - 560277     See in Manteia.
RefSeq - NM_001122858
RefSeq Peptide - NP_001116330
swissprot - E9QGP2
swissprot - E9QCA1
ZFIN ID - ZDB-GENE-060130-154
Ensembl - ENSDARG00000007988
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MASP2ENSGALG00000003016Gallus gallus
 MASP2ENSG00000009724Homo sapiens
 Masp2ENSMUSG00000028979Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
masp1 / mannan-binding lectin serine peptidase 1 / P48740* / P98064* / Mus musculus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant 1, mRNA.*ENSDARG0000006872642
c1r / complement component 1, r subcomponent / C1S* / P09871* / complement C1s*ENSDARG0000010024835
pamr1 / peptidase domain containing associated with muscle regeneration 1 / Q6UXH9* / Q8BU25* / Inactive serine protease PAMR1 *ENSDARG0000009348021
wu:fd46c06 / C1S* / P09871* / complement C1s*ENSDARG0000010209421
si:ch211-102l7.3 / PAMR1 (1 of many) / PAMR1* / Q6UXH9* / Q8BU25* / Inactive serine protease PAMR1 * / peptidase domain containing associated with muscle regeneration 1*ENSDARG0000010318419
CABZ01044048.1ENSDARG0000001146318
c1s / complement component 1, s subcomponentENSDARG0000010059918
f9a / coagulation factor IXa / F9* / P16294* / P00740* / coagulation factor IX* / Coagulation factor IX Coagulation factor IXa light chain Coagulation factor IXa heavy chain*ENSDARG0000001009718
f10 / coagulation factor X / O88947* / P00742* / Coagulation factor X Factor X light chain Factor X heavy chain Activated factor Xa heavy chain*ENSDARG0000008858118
proca / protein C (inactivator of coagulation factors Va and VIIIa), a / PROC* / P33587* / P04070* / protein C, inactivator of coagulation factors Va and VIIIa* / Vitamin K-dependent protei...ENSDARG0000003825818
zgc:163025 / F7 (1 of many) / F7* / P08709* / P70375* / coagulation factor VII* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSDARG0000010078218
proca / protein C (inactivator of coagulation factors Va and VIIIa), a / PROC* / P33587* / P04070* / protein C, inactivator of coagulation factors Va and VIIIa* / Vitamin K-dependent protei...ENSDARG0000009307918
f9b / coagulation factor IXb / F9* / P16294* / P00740* / coagulation factor IX* / Coagulation factor IX Coagulation factor IXa light chain Coagulation factor IXa heavy chain*ENSDARG0000002949318
f7 / coagulation factor VII / P08709* / P70375* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSDARG0000003486217
f7i / coagulation factor VIIi / F7* / P70375* / P08709* / coagulation factor VII* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSDARG0000007582716
proza / protein Z, vitamin K-dependent plasma glycoprotein a / PROZ* / P22891* / protein Z, vitamin K dependent plasma glycoprotein*ENSDARG0000003778314
prozb / protein Z, vitamin K-dependent plasma glycoprotein b / PROZ* / P22891* / Q9CQW3* / protein Z, vitamin K dependent plasma glycoprotein*ENSDARG0000007690012
hp / haptoglobin / HPR* / P00738* / P00739* / Q61646* / haptoglobin-related protein* / Haptoglobin Haptoglobin alpha chain Haptoglobin beta chain*ENSDARG0000005189010


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000436  Sushi/SCR/CCP domain
 IPR000859  CUB domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR001881  EGF-like calcium-binding domain
 IPR009003  Peptidase S1, PA clan
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001867 complement activation, lectin pathway IEA
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Lectin pathway of complement activation
Initial triggering of complement


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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