ENSDARG00000008880


Danio rerio

Features
Gene ID: ENSDARG00000008880
  
Biological name :usp28
  
Synonyms : ubiquitin specific peptidase 28 / usp28
  
Possible biological names infered from orthology : Q5I043 / Q96RU2
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 23050310
Gene end: 23110930
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000123445
Ensembl peptide - ENSDARP00000012821
Ensembl peptide - ENSDARP00000150612
Ensembl peptide - ENSDARP00000150990
swissprot - E9QC12
swissprot - E7FD72
ZFIN ID - ZDB-GENE-041008-142
Ensembl - ENSDARG00000008880
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP28ENSGALG00000006969Gallus gallus
 USP28ENSG00000048028Homo sapiens
 Usp28ENSMUSG00000032267Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
usp25 / ubiquitin specific peptidase 25 / P57080* / Q9UHP3*ENSDARG0000001231442


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR009060  UBA-like superfamily
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0021551 central nervous system morphogenesis IMP
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000155 somite somite fused with somite , abnormal
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 ZFA:0001114 head head damaged , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
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 ZFA:0001117 post-vent region post-vent region curled , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007241 mycb / Q7ZVS9 / MYC proto-oncogene, bHLH transcription factor b / MYC* / Bmyc* / P01106* / P01108* / Q6P8Z1* / Protein B-Myc * / myelocytomatosis oncogene* / MYC proto-oncogene, bHLH transc...  / complex






 

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