ENSDARG00000009870


Danio rerio

Features
Gene ID: ENSDARG00000009870
  
Biological name :mapk8b
  
Synonyms : mapk8b / mitogen-activated protein kinase 8b / Q9DGD9
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 2505519
Gene end: 2522487
  
Corresponding Affymetrix probe sets: Dr.10450.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000080945
Ensembl peptide - ENSDARP00000115805
Ensembl peptide - ENSDARP00000111769
Ensembl peptide - ENSDARP00000012611
NCBI entrez gene - 65236     See in Manteia.
swissprot - E9QJ67
swissprot - E9QB50
swissprot - F1RCB7
swissprot - Q9DGD9
ZFIN ID - ZDB-GENE-010202-1
Ensembl - ENSDARG00000009870
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mapk8a / mitogen-activated protein kinase 8aENSDARG0000003188893
mapk10 / mitogen-activated protein kinase 10 / P53779* / mitogen-activated protein kinase 10 isoform 1x *ENSDARG0000010273083
mapk9 / mitogen-activated protein kinase 9 / P45984* / Q9WTU6*ENSDARG0000007736474
Q9DGE2 / mapk14a / mitogen-activated protein kinase 14a / P47811* / Q16539* / MAPK14* / mitogen-activated protein kinase 14*ENSDARG0000000085744
mapk13 / mitogen-activated protein kinase 13ENSDARG0000005847043
mapk11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*ENSDARG0000004583643
mapk14b / mitogen-activated protein kinase 14b / Q16539* / MAPK14* / P47811* / mitogen-activated protein kinase 14*ENSDARG0000002872143
zgc:171775ENSDARG0000005838142
O42376 / mapk12a / mitogen-activated protein kinase 12a / O08911* / MAPK12* / P53778* / mitogen-activated protein kinase 12*ENSDARG0000004202142
mapk12b / mitogen-activated protein kinase 12b / P53778* / MAPK12* / O08911* / mitogen-activated protein kinase 12*ENSDARG0000000640941
BX324164.5 / MAPK13* / O15264* / mitogen-activated protein kinase 13*ENSDARG0000011014313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003527  Mitogen-activated protein (MAP) kinase, conserved site
 IPR008271  Serine/threonine-protein kinase, active site
 IPR008351  Mitogen-activated protein (MAP) kinase, JNK
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007254 JNK cascade IMP
 biological_processGO:0007258 JUN phosphorylation IEA
 biological_processGO:0009612 response to mechanical stimulus IBA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IBA
 biological_processGO:0048263 determination of dorsal identity IMP
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048666 neuron development IBA
 biological_processGO:0071310 cellular response to organic substance IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004705 JUN kinase activity IBA
 molecular_functionGO:0004707 MAP kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
Show

 ZFA:0000101 diencephalon diencephalon spatial pattern , abnormal
diencephalon right side spatial pattern , abnormal
Show

 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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