ENSDARG00000102730


Danio rerio

Features
Gene ID: ENSDARG00000102730
  
Biological name :mapk10
  
Synonyms : mapk10 / mitogen-activated protein kinase 10
  
Possible biological names infered from orthology : mitogen-activated protein kinase 10 isoform 1x / P53779
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 9576176
Gene end: 9713292
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131673
Ensembl peptide - ENSDARP00000139912
Ensembl peptide - ENSDARP00000135881
Ensembl peptide - ENSDARP00000134326
Ensembl peptide - ENSDARP00000133961
Ensembl peptide - ENSDARP00000133641
Ensembl peptide - ENSDARP00000129891
NCBI entrez gene - 569698     See in Manteia.
RefSeq - NM_001318321
RefSeq - NM_001037701
RefSeq - XM_005161474
RefSeq - NM_001318318
RefSeq - NM_001318319
RefSeq Peptide - NP_001305247
RefSeq Peptide - NP_001305248
RefSeq Peptide - NP_001305250
RefSeq Peptide - NP_001032790
swissprot - A0A0R4IN30
swissprot - A0A0R4IKK9
swissprot - A0A0R4IJM3
swissprot - A0A0R4IB91
swissprot - A0A0R4I9H8
swissprot - Q32LV0
ZFIN ID - ZDB-GENE-051120-117
Ensembl - ENSDARG00000102730
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAPK10ENSGALG00000011109Gallus gallus
 MAPK10ENSG00000109339Homo sapiens
 Mapk10ENSMUSG00000046709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mapk8a / mitogen-activated protein kinase 8aENSDARG0000003188874
mapk8b / Q9DGD9 / mitogen-activated protein kinase 8bENSDARG0000000987068
mapk9 / mitogen-activated protein kinase 9 / P45984* / Q9WTU6*ENSDARG0000007736468
mapk11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*ENSDARG0000004583637
mapk13 / mitogen-activated protein kinase 13ENSDARG0000005847037
mapk14b / mitogen-activated protein kinase 14b / Q16539* / MAPK14* / P47811* / mitogen-activated protein kinase 14*ENSDARG0000002872136
Q9DGE2 / mapk14a / mitogen-activated protein kinase 14a / P47811* / Q16539* / MAPK14* / mitogen-activated protein kinase 14*ENSDARG0000000085736
mapk12b / mitogen-activated protein kinase 12b / P53778* / MAPK12* / O08911* / mitogen-activated protein kinase 12*ENSDARG0000000640935
O42376 / mapk12a / mitogen-activated protein kinase 12a / O08911* / MAPK12* / P53778* / mitogen-activated protein kinase 12*ENSDARG0000004202135
zgc:171775ENSDARG0000005838134
BX324164.5 / MAPK13* / O15264* / mitogen-activated protein kinase 13*ENSDARG0000011014311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003527  Mitogen-activated protein (MAP) kinase, conserved site
 IPR008271  Serine/threonine-protein kinase, active site
 IPR008351  Mitogen-activated protein (MAP) kinase, JNK
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0048484 enteric nervous system development IMP
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004707 MAP kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activation of the AP-1 family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005775 enteric neuron enteric neuron decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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