ENSGALG00000011109


Gallus gallus

Features
Gene ID: ENSGALG00000011109
  
Biological name :MAPK10
  
Synonyms : Gallus gallus mitogen-activated protein kinase 10 (MAPK10), transcript variant 1, mRNA. / MAPK10
  
Possible biological names infered from orthology : mitogen-activated protein kinase 10 / mitogen-activated protein kinase 10 isoform 1x / P53779
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 46251251
Gene end: 46350676
  
Corresponding Affymetrix probe sets: Gga.1630.1.S1_x_at (Chicken Array)   GgaAffx.7042.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018075
Ensembl peptide - ENSGALP00000057620
NCBI entrez gene - 422592     See in Manteia.
RefSeq - XM_420551
RefSeq - XM_004941105
RefSeq - XM_004941106
RefSeq - XM_004941107
RefSeq - XM_015276496
RefSeq - NM_001318224
RefSeq - NM_001318225
RefSeq - XM_004941103
RefSeq - XM_004941104
RefSeq Peptide - NP_001305154
RefSeq Peptide - NP_001305153
swissprot - E1C8C5
swissprot - A0A1D5PXC6
Ensembl - ENSGALG00000011109
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapk10ENSDARG00000102730Danio rerio
 MAPK10ENSG00000109339Homo sapiens
 Mapk10ENSMUSG00000046709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAPK8 / mitogen-activated protein kinase 8 / P45983* / Q91Y86*ENSGALG0000000610975
MAPK9 / P79996 / Mitogen-activated protein kinase 9 / P45984* / Q9WTU6*ENSGALG0000003909970
MAPK11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*ENSGALG0000004002339
MAPK12 / mitogen-activated protein kinase 12 / O08911* / P53778*ENSGALG0000001938436
MAPK13 / mitogen-activated protein kinase 13 / O15264* / Q9Z1B7*ENSGALG0000003096630
MAPK14 / mitogen-activated protein kinase 14 / P47811* / Q16539*ENSGALG0000004283319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003527  Mitogen-activated protein (MAP) kinase, conserved site
 IPR008271  Serine/threonine-protein kinase, active site
 IPR008351  Mitogen-activated protein (MAP) kinase, JNK
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007254 JNK cascade IBA
 biological_processGO:0007258 JUN phosphorylation IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0048666 neuron development IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004705 JUN kinase activity IBA
 molecular_functionGO:0004707 MAP kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activation of the AP-1 family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000032178 MAP2K4 / mitogen-activated protein kinase kinase 4 / P45985* / P47809* / Dual specificity mitogen-activated protein kinase kinase 4 *  / reaction






 

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