ENSGALG00000019384


Gallus gallus

Features
Gene ID: ENSGALG00000019384
  
Biological name :MAPK12
  
Synonyms : MAPK12 / mitogen-activated protein kinase 12
  
Possible biological names infered from orthology : O08911 / P53778
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 20367873
Gene end: 20396572
  
Corresponding Affymetrix probe sets: Gga.10214.1.S1_at (Chicken Array)   Gga.10214.1.S1_s_at (Chicken Array)   Gga.13597.1.S1_at (Chicken Array)   Gga.13829.1.S1_at (Chicken Array)   GgaAffx.22647.3.S1_at (Chicken Array)   GgaAffx.22647.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014011
Ensembl peptide - ENSGALP00000044005
NCBI entrez gene - 769763     See in Manteia.
RefSeq - XM_001233061
swissprot - A0A1D5NUI7
swissprot - F1NLU9
Ensembl - ENSGALG00000019384
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapk12bENSDARG00000006409Danio rerio
 O42376ENSDARG00000042021Danio rerio
 MAPK12ENSG00000188130Homo sapiens
 Mapk12ENSMUSG00000022610Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAPK11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*ENSGALG0000004002362
MAPK13 / mitogen-activated protein kinase 13 / O15264* / Q9Z1B7*ENSGALG0000003096654
MAPK10 / Gallus gallus mitogen-activated protein kinase 10 (MAPK10), transcript variant 1, mRNA. / P53779* / mitogen-activated protein kinase 10* / mitogen-activated protein kinase 10 isoform 1x *ENSGALG0000001110947
MAPK8 / mitogen-activated protein kinase 8 / P45983* / Q91Y86*ENSGALG0000000610946
MAPK9 / P79996 / Mitogen-activated protein kinase 9 / P45984* / Q9WTU6*ENSGALG0000003909945
MAPK14 / mitogen-activated protein kinase 14 / P47811* / Q16539*ENSGALG0000004283332


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003527  Mitogen-activated protein (MAP) kinase, conserved site
 IPR008352  Mitogen-activated protein (MAP) kinase p38-like
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0045445 myoblast differentiation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004707 MAP kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
CDO in myogenesis
DSCAM interactions
VEGFA-VEGFR2 Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004796 CDC42 / Q90694 / Cell division control protein 42 homolog / P60766* / P60953* / cell division cycle 42* / Cell division control *  / complex
 ENSGALG00000003875 ABL1 / ABL proto-oncogene 1, non-receptor tyrosine kinase / P00519* / P00520* / c-abl oncogene 1, non-receptor tyrosine kinase*  / complex
 ENSGALG00000015152 BOC / BOC cell adhesion associated, oncogene regulated / Q9BWV1*  / complex
 ENSGALG00000035419 CDON / cell adhesion associated, oncogene regulated / Q32MD9* / Q4KMG0* / Cell adhesion molecule-related/down-regulated by oncos *  / complex
 ENSGALG00000015132 CDH2 / P10288 / Cadherin-2 / P15116* / P19022*  / complex
 ENSGALG00000030040 CDH15 / cadherin 15 / P33146* / P55291*  / complex
 ENSGALG00000002447 CTNNA1 / catenin alpha 1 / P26231* / P35221*  / complex
 ENSGALG00000014645 MEF2C / myocyte enhancer factor 2C / Q06413* / Q8CFN5* / Mus musculus myocyte enhancer factor 2C (Mef2c), transcript variant 14, mRNA.*  / complex / reaction
 ENSGALG00000032366 MEF2A / myocyte enhancer factor 2A / Q02078* / Q60929* / Mus musculus myocyte enhancer factor 2A (Mef2a), transcript variant 7, mRNA.*  / complex / reaction






 

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