ENSDARG00000077364


Danio rerio

Features
Gene ID: ENSDARG00000077364
  
Biological name :mapk9
  
Synonyms : mapk9 / mitogen-activated protein kinase 9
  
Possible biological names infered from orthology : P45984 / Q9WTU6
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 32349190
Gene end: 32374656
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000099157
NCBI entrez gene - 100149273     See in Manteia.
swissprot - E9QE29
ZFIN ID - ZDB-GENE-091117-28
Ensembl - ENSDARG00000077364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAPK9ENSGALG00000039099Gallus gallus
 MAPK9ENSG00000050748Homo sapiens
 Mapk9ENSMUSG00000020366Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mapk10 / mitogen-activated protein kinase 10 / P53779* / mitogen-activated protein kinase 10 isoform 1x *ENSDARG0000010273077
mapk8a / mitogen-activated protein kinase 8aENSDARG0000003188873
mapk8b / Q9DGD9 / mitogen-activated protein kinase 8bENSDARG0000000987068
Q9DGE2 / mapk14a / mitogen-activated protein kinase 14a / P47811* / Q16539* / MAPK14* / mitogen-activated protein kinase 14*ENSDARG0000000085741
mapk14b / mitogen-activated protein kinase 14b / Q16539* / MAPK14* / P47811* / mitogen-activated protein kinase 14*ENSDARG0000002872141
mapk11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*ENSDARG0000004583640
mapk13 / mitogen-activated protein kinase 13ENSDARG0000005847039
mapk12b / mitogen-activated protein kinase 12b / P53778* / MAPK12* / O08911* / mitogen-activated protein kinase 12*ENSDARG0000000640939
O42376 / mapk12a / mitogen-activated protein kinase 12a / O08911* / MAPK12* / P53778* / mitogen-activated protein kinase 12*ENSDARG0000004202139
zgc:171775ENSDARG0000005838138
BX324164.5 / MAPK13* / O15264* / mitogen-activated protein kinase 13*ENSDARG0000011014312


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003527  Mitogen-activated protein (MAP) kinase, conserved site
 IPR008271  Serine/threonine-protein kinase, active site
 IPR008351  Mitogen-activated protein (MAP) kinase, JNK
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0060027 convergent extension involved in gastrulation IMP
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004707 MAP kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activation of the AP-1 family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord increased width , abnormal
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 ZFA:0000155 somite somite increased width , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008279 map2k7 / mitogen-activated protein kinase kinase 7 / O14733* / Q8CE90* / Dual specificity mitogen-activated protein kinase kinase 7 *  / reaction
 ENSDARG00000043531 jun / Jun proto-oncogene, AP-1 transcription factor subunit / P05412* / P05627* / jun proto-oncogene*  / reaction
 ENSDARG00000023903 atf2 / activating transcription factor 2 / P15336* / P16951* / Cyclic AMP-dependent transcription factor ATF-2 *  / reaction






 

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