ENSDARG00000008279


Danio rerio

Features
Gene ID: ENSDARG00000008279
  
Biological name :map2k7
  
Synonyms : map2k7 / mitogen-activated protein kinase kinase 7
  
Possible biological names infered from orthology : Dual specificity mitogen-activated protein kinase kinase 7 / O14733 / Q8CE90
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 45839927
Gene end: 45856178
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000116807
Ensembl peptide - ENSDARP00000145176
Ensembl peptide - ENSDARP00000143840
Ensembl peptide - ENSDARP00000048190
NCBI entrez gene - 560913     See in Manteia.
RefSeq - NM_001190306
RefSeq - XM_005160049
RefSeq Peptide - NP_001177235
swissprot - F6P5Q1
swissprot - D6RRB7
swissprot - A0A286YA49
ZFIN ID - ZDB-GENE-090312-186
Ensembl - ENSDARG00000008279
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAP2K7ENSG00000076984Homo sapiens
 Map2k7ENSMUSG00000002948Mus musculus
 Map2k7ENSMUSG00000109061Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
map2k4a / mitogen-activated protein kinase kinase 4a / P45985* / MAP2K4* / P47809* / mitogen-activated protein kinase kinase 4* / Dual specificity mitogen-activated protein kinase kinase 4 *ENSDARG0000006358339
map2k4b / mitogen-activated protein kinase kinase 4b / P45985* / MAP2K4* / P47809* / mitogen-activated protein kinase kinase 4* / Dual specificity mitogen-activated protein kinase kinase 4 *ENSDARG0000007717738
map2k6 / Q9DGE0 / mitogen-activated protein kinase kinase 6 / P52564*ENSDARG0000009918433
map2k1 / mitogen-activated protein kinase kinase 1 / P31938* / Q02750* / Dual specificity mitogen-activated protein kinase kinase 1 *ENSDARG0000000782529
map2k2b / mitogen-activated protein kinase kinase 2b / P36507* / MAP2K2* / Q63932* / AC011005.1* / mitogen-activated protein kinase kinase 2* / Mus musculus mitogen-activated protein kinase...ENSDARG0000006891829
map2k2a / mitogen-activated protein kinase kinase 2a / P36507* / MAP2K2* / Q63932* / AC011005.1* / mitogen-activated protein kinase kinase 2* / Mus musculus mitogen-activated protein kinase...ENSDARG0000000660929
map2k5 / mitogen-activated protein kinase kinase 5 / Q13163* / Q9WVS7* / Dual specificity mitogen-activated protein kinase kinase 5 *ENSDARG0000001185127


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite irregular spatial pattern , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000077364 mapk9 / mitogen-activated protein kinase 9 / P45984* / Q9WTU6*  / reaction
 ENSDARG00000098405 map3k1 / mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase / Q13233* / mitogen-activated protein kinase kinase kinase 1*  / reaction






 

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