ENSDARG00000098405


Danio rerio

Features
Gene ID: ENSDARG00000098405
  
Biological name :map3k1
  
Synonyms : map3k1 / mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  
Possible biological names infered from orthology : mitogen-activated protein kinase kinase kinase 1 / Q13233
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 5954787
Gene end: 6004863
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000136414
Ensembl peptide - ENSDARP00000141257
Ensembl peptide - ENSDARP00000150715
swissprot - A0A0R4IQU7
swissprot - A0A0R4IZ86
ZFIN ID - ZDB-GENE-090313-412
Ensembl - ENSDARG00000098405
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAP3K1ENSGALG00000014718Gallus gallus
 MAP3K1ENSG00000095015Homo sapiens
 Map3k1ENSMUSG00000021754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
map3k2 / mitogen-activated protein kinase kinase kinase 2 / Q9Y2U5*ENSDARG0000006288413
map3k3 / mitogen-activated protein kinase kinase kinase 3 / Q61084* / Q99759*ENSDARG0000006034812
map3k14a / mitogen-activated protein kinase kinase kinase 14a / Q9WUL6* / Q99558* / MAP3K14* / mitogen-activated protein kinase kinase kinase 14*ENSDARG000000740607
map3k8 / mitogen-activated protein kinase kinase kinase 8 / P41279* / Q07174*ENSDARG000000617107
map3k19 / mitogen-activated protein kinase kinase kinase 19 / E9Q3S4* / Q56UN5*ENSDARG000000942727
arf2b / map3k14b / mitogen-activated protein kinase kinase kinase 14b / Q9WUL6* / Q99558* / MAP3K14* / mitogen-activated protein kinase kinase kinase 14*ENSDARG000000565826
map3k20 / mitogen-activated protein kinase kinase kinase 20ENSDARG000000742193


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001841  Zinc finger, RING-type
 IPR007527  Zinc finger, SWIM-type
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016024  Armadillo-type fold
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
MyD88:Mal cascade initiated on plasma membrane
FCERI mediated MAPK activation
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88 cascade initiated on plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000028058 traf6 / Q6IWL4 / TNF receptor-associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSDARG00000008279 map2k7 / mitogen-activated protein kinase kinase 7 / O14733* / Q8CE90* / Dual specificity mitogen-activated protein kinase kinase 7 *  / reaction






 

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