ENSGALG00000014718


Gallus gallus

Features
Gene ID: ENSGALG00000014718
  
Biological name :MAP3K1
  
Synonyms : MAP3K1 / mitogen-activated protein kinase kinase kinase 1
  
Possible biological names infered from orthology : Q13233
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 17406003
Gene end: 17465113
  
Corresponding Affymetrix probe sets: Gga.13126.1.S1_at (Chicken Array)   GgaAffx.9341.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050840
Ensembl peptide - ENSGALP00000023686
NCBI entrez gene - 427144     See in Manteia.
RefSeq - XM_015277579
RefSeq - XM_015277577
RefSeq - XM_015277578
RefSeq - XM_015277575
RefSeq - XM_015277576
swissprot - F1N938
swissprot - A0A1D5PDJ5
Ensembl - ENSGALG00000014718
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map3k1ENSDARG00000098405Danio rerio
 MAP3K1ENSG00000095015Homo sapiens
 Map3k1ENSMUSG00000021754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAP3K19 / mitogen-activated protein kinase kinase kinase 19 / E9Q3S4* / Q56UN5*ENSGALG0000002845711
MAP3K3 / mitogen-activated protein kinase kinase kinase 3 / Q61084* / Q99759*ENSGALG0000000052511
MAPKKK3LENSGALG0000000588410
MAP3K14 / mitogen-activated protein kinase kinase kinase 14 / Q99558* / Q9WUL6*ENSGALG000000006858
MAP3K8 / mitogen-activated protein kinase kinase kinase 8 / P41279* / Q07174*ENSGALG000000073566
MAP3K2* / Q9Y2U5* / mitogen-activated protein kinase kinase kinase 2*ENSGALG000000115024


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001841  Zinc finger, RING-type
 IPR007527  Zinc finger, SWIM-type
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA


Pathways (from Reactome)
Pathway description
MyD88:Mal cascade initiated on plasma membrane
FCERI mediated MAPK activation
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88 cascade initiated on plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSGALG00000032178 MAP2K4 / mitogen-activated protein kinase kinase 4 / P45985* / P47809* / Dual specificity mitogen-activated protein kinase kinase 4 *  / reaction






 

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