ENSGALG00000000685


Gallus gallus

Features
Gene ID: ENSGALG00000000685
  
Biological name :MAP3K14
  
Synonyms : MAP3K14 / mitogen-activated protein kinase kinase kinase 14
  
Possible biological names infered from orthology : Q99558 / Q9WUL6
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 1563067
Gene end: 1577397
  
Corresponding Affymetrix probe sets: GgaAffx.428.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039949
NCBI entrez gene - 419964     See in Manteia.
RefSeq - XM_015299228
RefSeq - NM_001030927
RefSeq - XM_015299225
RefSeq - XM_015299226
RefSeq - XM_015299223
RefSeq - XM_015299224
RefSeq Peptide - NP_001026098
swissprot - F1NMZ5
Ensembl - ENSGALG00000000685
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arf2bENSDARG00000056582Danio rerio
 map3k14aENSDARG00000074060Danio rerio
 Q99558ENSG00000006062Homo sapiens
 Q9WUL6ENSMUSG00000020941Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAP3K1 / mitogen-activated protein kinase kinase kinase 1 / Q13233*ENSGALG0000001471814
MAP3K3 / mitogen-activated protein kinase kinase kinase 3 / Q61084* / Q99759*ENSGALG0000000052513
MAPKKK3LENSGALG0000000588412
MAP3K19 / mitogen-activated protein kinase kinase kinase 19 / E9Q3S4* / Q56UN5*ENSGALG0000002845711
MAP3K8 / mitogen-activated protein kinase kinase kinase 8 / P41279* / Q07174*ENSGALG0000000735611
MAP3K2* / Q9Y2U5* / mitogen-activated protein kinase kinase kinase 2*ENSGALG000000115025


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017425  Mitogen-activated protein (MAP) kinase kinase kinase 14
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0038061 NIK/NF-kappaB signaling IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004704 NF-kappaB-inducing kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
CD28 dependent PI3K/Akt signaling
Dectin-1 mediated noncanonical NF-kB signaling
TNFR2 non-canonical NF-kB pathway
NIK-->noncanonical NF-kB signaling
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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