ENSDARG00000010415


Danio rerio

Features
Gene ID: ENSDARG00000010415
  
Biological name :sirt4
  
Synonyms : sirt4 / sirtuin 4
  
Possible biological names infered from orthology : NAD-dependent protein lipoamidase sirtuin-4, mitochondrial / Q8R216 / Q9Y6E7
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 40877394
Gene end: 40885496
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000027611
Ensembl peptide - ENSDARP00000127911
Ensembl peptide - ENSDARP00000150685
Ensembl peptide - ENSDARP00000151571
NCBI entrez gene - 791628     See in Manteia.
RefSeq - NM_001005988
RefSeq - XM_005166066
RefSeq - XM_005166068
RefSeq Peptide - NP_001005988
swissprot - X1WCG8
swissprot - F1QHM6
ZFIN ID - ZDB-GENE-041010-65
Ensembl - ENSDARG00000010415
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SIRT4ENSGALG00000007244Gallus gallus
 SIRT4ENSG00000089163Homo sapiens
 Sirt4ENSMUSG00000029524Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sirt5 / Q6DHI5 / sirtuin 5 / Q8K2C6* / Q9NXA8* / NAD-dependent protein deacylase sirtuin-5, mitochondrial *ENSDARG0000003968423
sirt1 / sirtuin 1 / Q96EB6*ENSDARG0000006806422


Protein motifs (from Interpro)
Interpro ID Name
 IPR003000  Sirtuin family
 IPR026587  Sirtuin, class II
 IPR026590  Sirtuin family, catalytic core domain
 IPR029035  DHS-like NAD/FAD-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006471 protein ADP-ribosylation IEA
 biological_processGO:0006476 protein deacetylation IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0034979 NAD-dependent protein deacetylase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070403 NAD+ binding IEA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000101074 glud1b / glutamate dehydrogenase 1b / GLUD1* / GLUD2* / P49448* / P00367* / P26443* / glutamate dehydrogenase 1* / glutamate dehydrogenase 2* / Glutamate dehydrogenase 1, mitochondrial *  / reaction






 

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