ENSDARG00000039684


Danio rerio

Features
Gene ID: ENSDARG00000039684
  
Biological name :sirt5
  
Synonyms : Q6DHI5 / sirt5 / sirtuin 5
  
Possible biological names infered from orthology : NAD-dependent protein deacylase sirtuin-5, mitochondrial / Q8K2C6 / Q9NXA8
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 7052870
Gene end: 7069612
  
Corresponding Affymetrix probe sets: Dr.16341.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000040792
NCBI entrez gene - 436878     See in Manteia.
swissprot - Q6DHI5
ZFIN ID - ZDB-GENE-040718-349
Ensembl - ENSDARG00000039684
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SIRT5ENSGALG00000012692Gallus gallus
 SIRT5ENSG00000124523Homo sapiens
 Sirt5ENSMUSG00000054021Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sirt1 / sirtuin 1 / Q96EB6*ENSDARG0000006806425
sirt4 / sirtuin 4 / Q8R216* / Q9Y6E7* / NAD-dependent protein lipoamidase sirtuin-4, mitochondrial *ENSDARG0000001041524


Protein motifs (from Interpro)
Interpro ID Name
 IPR003000  Sirtuin family
 IPR026590  Sirtuin family, catalytic core domain
 IPR026591  Sirtuin, catalytic core small domain superfamily
 IPR027546  Sirtuin, class III
 IPR029035  DHS-like NAD/FAD-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010566 regulation of ketone biosynthetic process ISS
 biological_processGO:0036047 peptidyl-lysine demalonylation ISS
 biological_processGO:0036048 protein desuccinylation ISS
 biological_processGO:0036049 peptidyl-lysine desuccinylation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036054 protein-malonyllysine demalonylase activity ISS
 molecular_functionGO:0036055 protein-succinyllysine desuccinylase activity ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070403 NAD+ binding ISS


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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