ENSDARG00000010472


Danio rerio

Features
Gene ID: ENSDARG00000010472
  
Biological name :atp1a2a
  
Synonyms : atp1a2a / ATPase Na+/K+ transporting subunit alpha 2
  
Possible biological names infered from orthology : ATP1A2 / P50993 / Q6PIE5 / Sodium/potassium-transporting ATPase subunit alpha-2
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 44203075
Gene end: 44255537
  
Corresponding Affymetrix probe sets: Dr.10438.1.S1_at (Zebrafish Array)   NM_131683_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000087730
Ensembl peptide - ENSDARP00000024272
NCBI entrez gene - 64609     See in Manteia.
RefSeq - NM_131683
RefSeq Peptide - NP_571758
swissprot - B0S5Q5
ZFIN ID - ZDB-GENE-001212-6
Ensembl - ENSDARG00000010472
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP1A2ENSG00000018625Homo sapiens
 Atp1a2ENSMUSG00000007097Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atp1a1b / ATPase Na+/K+ transporting subunit alpha 1b / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPase subunit alpha-1 *ENSDARG0000001985684
atp1a1a.1 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 1 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000000279184
atp1a3a / ATPase Na+/K+ transporting subunit alpha 3a / P13637* / ATP1A3* / Q6PIC6* / AC010616.2* / ATPase Na+/K+ transporting subunit alpha 3* / Sodium/potassium-transporting ATPase subuni...ENSDARG0000001825983
atp1a1a.4 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 4 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000000187083
atp1a3b / ATPase Na+/K+ transporting subunit alpha 3b / P13637* / ATP1A3* / Q6PIC6* / AC010616.2* / ATPase Na+/K+ transporting subunit alpha 3* / Sodium/potassium-transporting ATPase subuni...ENSDARG0000010413983
atp1a1a.3 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000003913178
atp1a1a.2 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000000773977
atp1a1a.5 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 5 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000004025274
atp2a3 / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 / Q64518* / Q93084* / Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 *ENSDARG0000006097828
si:dkey-28b4.8ENSDARG0000000284028
atp2a2a / atp2a2b / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a / ATP2A2* / O55143* / P16615* / Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 * / ATPase sarcoplasmi...ENSDARG0000000512228
atp2c1 / ATPase secretory pathway Ca2+ transporting 1 / P98194* / Q80XR2* / Calcium-transporting ATPase type 2C member 1 *ENSDARG0000006019728
atp2a2a / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a / ATP2A2* / O55143* / P16615* / Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 * / ATPase sarcoplasmic/endoplas...ENSDARG0000002943928
atp2a1l / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, likeENSDARG0000003545827
atp2a1 / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1ENSDARG0000002057427


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR004014  Cation-transporting P-type ATPase, N-terminal
 IPR005775  P-type ATPase subfamily IIC, subunit alpha
 IPR006068  Cation-transporting P-type ATPase, C-terminal
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0001966 thigmotaxis IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0010084 specification of animal organ axis polarity IMP
 biological_processGO:0010248 establishment or maintenance of transmembrane electrochemical gradient IEA
 biological_processGO:0042044 fluid transport IMP
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration IMP
 biological_processGO:0060047 heart contraction IMP
 biological_processGO:0061371 determination of heart left/right asymmetry IMP
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005391 sodium:potassium-exchanging ATPase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium movement quality , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000112 gut gut mislocalised , abnormal
Show

 ZFA:0000114 heart heart mislocalised , abnormal
Show

 ZFA:0000123 liver liver mislocalised , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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