ENSDARG00000013430


Danio rerio

Features
Gene ID: ENSDARG00000013430
  
Biological name :bhmt
  
Synonyms : betaine-homocysteine methyltransferase / bhmt
  
Possible biological names infered from orthology : betaine--homocysteine S-methyltransferase / Betaine--homocysteine S-methyltransferase 1 / betaine--homocysteine S-methyltransferase 2 / BHMT2 / Gm5096 / O35490 / predicted gene 5096 / Q91WS4 / Q93088 / Q9H2M3 / S-methylmethionine--homocysteine S-methyltransferase BHMT2
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 40408
Gene end: 45920
  
Corresponding Affymetrix probe sets: Dr.2596.1.S1_a_at (Zebrafish Array)   Dr.2596.3.A1_at (Zebrafish Array)   NM_001012480_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040421
Ensembl peptide - ENSDARP00000145381
NCBI entrez gene - 322228     See in Manteia.
RefSeq - NM_001012480
RefSeq Peptide - NP_001012498
swissprot - F1QU55
ZFIN ID - ZDB-GENE-030131-947
Ensembl - ENSDARG00000013430
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000004518Gallus gallus
 BHMTENSG00000145692Homo sapiens
 BHMT2ENSG00000132840Homo sapiens
 BhmtENSMUSG00000074768Mus musculus
 Bhmt2ENSMUSG00000042118Mus musculus
 Gm5096ENSMUSG00000069324Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003726  Homocysteine-binding domain
 IPR017226  Betaine-homocysteine S-methyltransferase, BHMT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009086 methionine biosynthetic process IEA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047150 betaine-homocysteine S-methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Sulfur amino acid metabolism
Choline catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000123 liver liver decreased size , abnormal
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 ZFA:0000135 notochord notochord increased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
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 ZFA:0001249 exocrine pancreas exocrine pancreas decreased size , abnormal
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 ZFA:0001260 endocrine pancreas endocrine pancreas increased size , abnormal
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 ZFA:0001338 intestine intestine decreased size , abnormal
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 ZFA:0009102 pancreatic B cell pancreatic B cell increased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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