ENSG00000132840


Homo sapiens

Features
Gene ID: ENSG00000132840
  
Biological name :BHMT2
  
Synonyms : betaine--homocysteine S-methyltransferase 2 / BHMT2 / Q9H2M3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q14.1
Gene start: 79069717
Gene end: 79089466
  
Corresponding Affymetrix probe sets: 219902_at (Human Genome U133 Plus 2.0 Array)   230309_at (Human Genome U133 Plus 2.0 Array)   242169_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000255192
Ensembl peptide - ENSP00000430278
Ensembl peptide - ENSP00000430155
Ensembl peptide - ENSP00000428640
NCBI entrez gene - 23743     See in Manteia.
OMIM - 605932
RefSeq - NM_017614
RefSeq - NM_001178005
RefSeq Peptide - NP_001171476
RefSeq Peptide - NP_060084
swissprot - Q9H2M3
swissprot - E5RGH5
swissprot - A0A024RAQ0
swissprot - E5RH96
Ensembl - ENSG00000132840
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bhmtENSDARG00000013430Danio rerio
 ENSGALG00000004518Gallus gallus
 Bhmt2ENSMUSG00000042118Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BHMT / Q93088 / betaine--homocysteine S-methyltransferaseENSG0000014569278


Protein motifs (from Interpro)
Interpro ID Name
 IPR003726  Homocysteine-binding domain
 IPR017226  Betaine-homocysteine S-methyltransferase, BHMT
 IPR036589  Homocysteine-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000096 sulfur amino acid metabolic process TAS
 biological_processGO:0009086 methionine biosynthetic process IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0033477 S-methylmethionine metabolic process IDA
 biological_processGO:0046500 S-adenosylmethionine metabolic process IDA
 biological_processGO:0071267 L-methionine salvage IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047150 betaine-homocysteine S-methyltransferase activity IEA
 molecular_functionGO:0061627 S-methylmethionine-homocysteine S-methyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Sulfur amino acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132840 BHMT2 / Q9H2M3 / betaine--homocysteine S-methyltransferase 2  / complex






 

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