ENSG00000145692


Homo sapiens

Features
Gene ID: ENSG00000145692
  
Biological name :BHMT
  
Synonyms : betaine--homocysteine S-methyltransferase / BHMT / Q93088
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q14.1
Gene start: 79111779
Gene end: 79132290
  
Corresponding Affymetrix probe sets: 206119_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000274353
Ensembl peptide - ENSP00000428240
NCBI entrez gene - 635     See in Manteia.
OMIM - 602888
RefSeq - NM_001713
RefSeq Peptide - NP_001704
swissprot - E5RJH0
swissprot - Q93088
swissprot - V9HWA4
Ensembl - ENSG00000145692
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bhmtENSDARG00000013430Danio rerio
 ENSGALG00000004518Gallus gallus
 BhmtENSMUSG00000074768Mus musculus
 Gm5096ENSMUSG00000069324Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BHMT2 / Q9H2M3 / betaine--homocysteine S-methyltransferase 2ENSG0000013284069


Protein motifs (from Interpro)
Interpro ID Name
 IPR003726  Homocysteine-binding domain
 IPR017226  Betaine-homocysteine S-methyltransferase, BHMT
 IPR036589  Homocysteine-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000096 sulfur amino acid metabolic process TAS
 biological_processGO:0006479 protein methylation NAS
 biological_processGO:0006577 amino-acid betaine metabolic process IDA
 biological_processGO:0006579 amino-acid betaine catabolic process IEA
 biological_processGO:0009086 methionine biosynthetic process IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0042426 choline catabolic process TAS
 biological_processGO:0050666 regulation of homocysteine metabolic process NAS
 biological_processGO:0071267 L-methionine salvage IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047150 betaine-homocysteine S-methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Sulfur amino acid metabolism
Choline catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000145692 BHMT / Q93088 / betaine--homocysteine S-methyltransferase  / complex






 

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