ENSMUSG00000042118


Mus musculus

Features
Gene ID: ENSMUSG00000042118
  
Biological name :Bhmt2
  
Synonyms : Bhmt2 / Q91WS4 / S-methylmethionine--homocysteine S-methyltransferase BHMT2
  
Possible biological names infered from orthology : betaine--homocysteine S-methyltransferase 2 / Q9H2M3
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: C3
Gene start: 93655720
Gene end: 93674302
  
Corresponding Affymetrix probe sets: 10411147 (MoGene1.0st)   1418913_at (Mouse Genome 430 2.0 Array)   1418914_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015941
NCBI entrez gene - 64918     See in Manteia.
MGI - MGI:1891379
RefSeq - NM_022884
RefSeq Peptide - NP_075022
swissprot - Q91WS4
Ensembl - ENSMUSG00000042118
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bhmtENSDARG00000013430Danio rerio
 ENSGALG00000004518Gallus gallus
 BHMT2ENSG00000132840Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bhmt / O35490 / Betaine--homocysteine S-methyltransferase 1 / Q93088* / betaine--homocysteine S-methyltransferase*ENSMUSG0000007476875
Gm5096 / O35490 / predicted gene 5096 / BHMT* / Q93088* / betaine--homocysteine S-methyltransferase*ENSMUSG0000006932475


Protein motifs (from Interpro)
Interpro ID Name
 IPR003726  Homocysteine-binding domain
 IPR017226  Betaine-homocysteine S-methyltransferase, BHMT
 IPR036589  Homocysteine-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009086 methionine biosynthetic process ISO
 biological_processGO:0032259 methylation IEA
 biological_processGO:0033477 S-methylmethionine metabolic process IEA
 biological_processGO:0046500 S-adenosylmethionine metabolic process IEA
 biological_processGO:0071267 L-methionine salvage IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047150 betaine-homocysteine S-methyltransferase activity IEA
 molecular_functionGO:0061627 S-methylmethionine-homocysteine S-methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Sulfur amino acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000042118 Bhmt2 / Q91WS4 / S-methylmethionine--homocysteine S-methyltransferase BHMT2 / Q9H2M3* / betaine--homocysteine S-methyltransferase 2*  / complex






 

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