ENSDARG00000014373


Danio rerio

Features
Gene ID: ENSDARG00000014373
  
Biological name :ddx4
  
Synonyms : ddx4 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
  
Possible biological names infered from orthology : ATP-dependent RNA helicase DDX4 / DEAD-box helicase 4 / Q61496 / Q9NQI0
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 6884123
Gene end: 6905574
  
Corresponding Affymetrix probe sets: Dr.559.2.S1_a_at (Zebrafish Array)   NM_131057_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000111634
Ensembl peptide - ENSDARP00000096157
Ensembl peptide - ENSDARP00000110084
Ensembl peptide - ENSDARP00000125001
Ensembl peptide - ENSDARP00000123870
Ensembl peptide - ENSDARP00000124026
NCBI entrez gene - 30263     See in Manteia.
RefSeq - XM_005156453
RefSeq - XM_017357927
RefSeq - XM_021479102
RefSeq - XM_021479103
RefSeq - XM_021479104
RefSeq - XM_021479105
RefSeq - NM_131057
RefSeq - XM_017357926
RefSeq Peptide - NP_571132
swissprot - F8W4P0
swissprot - E7EZA2
swissprot - F1QSP5
swissprot - F1R6M3
swissprot - F8W3U8
swissprot - Q8QGG8
ZFIN ID - ZDB-GENE-990415-272
Ensembl - ENSDARG00000014373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX4ENSGALG00000014713Gallus gallus
 DDX4ENSG00000152670Homo sapiens
 Ddx4ENSMUSG00000021758Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ddx3a / DEAD (Asp-Glu-Ala-Asp) box helicase 3a / DDX3X* / DDX3Y* / O15523* / O00571* / P16381* / D1Pas1* / Q62167* / Q62095* / DEAD-box helicase 3, Y-linked* / DEAD-box helicase 3, X-linked...ENSDARG0000002057337
ddx3b / DEAD (Asp-Glu-Ala-Asp) box helicase 3b / DDX3X* / DDX3Y* / O15523* / O00571* / P16381* / D1Pas1* / Q62167* / Q62095* / DEAD-box helicase 3, Y-linked* / DEAD-box helicase 3, X-linked...ENSDARG0000000577437
ddx59 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 / Q5T1V6* / Q9DBN9* / DEAD-box helicase 59* / Probable ATP-dependent RNA helicase DDX59 *ENSDARG0000002217720
ddx1 / DEAD (Asp-Glu-Ala-Asp) box helicase 1 / Q91VR5* / Q92499* / DEAD-box helicase 1* / ATP-dependent RNA helicase DDX1 *ENSDARG0000003211716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008406 gonad development IEP
 cellular_componentGO:0043186 P granule IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000242 male organism male organism sterile , abnormal
Show

 ZFA:0000303 female organism female organism absent , abnormal
Show

 ZFA:0000413 gonad gonad absent , abnormal
gonad decreased amount , abnormal
gonad spatial pattern , abnormal
gonad decreased size , abnormal
gonad primordial germ cell decreased amount , abnormal
Show

 ZFA:0000598 testis testis lymphocyte increased amount , abnormal
testis absent , abnormal
testis decreased size , abnormal
Show

 ZFA:0005879 seminiferous tubule seminiferous tubule germ line cell absent , abnormal
Show

 ZFA:0009288 primordial germ cell primordial germ cell absent , abnormal
primordial germ cell vacuole increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr