ENSDARG00000005774


Danio rerio

Features
Gene ID: ENSDARG00000005774
  
Biological name :ddx3b
  
Synonyms : ddx3b / DEAD (Asp-Glu-Ala-Asp) box helicase 3b
  
Possible biological names infered from orthology : ATP-dependent RNA helicase DDX3X / ATP-dependent RNA helicase DDX3Y / D1Pas1 / DDX3X / DDX3Y / DEAD-box helicase 3, X-linked / DEAD-box helicase 3, Y-linked / O00571 / O15523 / P16381 / Putative ATP-dependent RNA helicase Pl10 / Q62095 / Q62167
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 59832786
Gene end: 59850404
  
Corresponding Affymetrix probe sets: Dr.5335.1.S1_at (Zebrafish Array)   Dr.5335.1.S2_at (Zebrafish Array)   NM_130941_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000092924
Ensembl peptide - ENSDARP00000128914
Ensembl peptide - ENSDARP00000129624
NCBI entrez gene - 30116     See in Manteia.
RefSeq - NM_130941
RefSeq Peptide - NP_571016
swissprot - F1RCB2
swissprot - X1WFB0
swissprot - X1WHB2
ZFIN ID - ZDB-GENE-980526-150
Ensembl - ENSDARG00000005774
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX3XENSGALG00000016231Gallus gallus
 DDX3XENSG00000215301Homo sapiens
 DDX3YENSG00000067048Homo sapiens
 D1Pas1ENSMUSG00000039224Mus musculus
 Ddx3xENSMUSG00000000787Mus musculus
 Ddx3yENSMUSG00000069045Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ddx3a / DEAD (Asp-Glu-Ala-Asp) box helicase 3a / DDX3X* / DDX3Y* / O15523* / O00571* / P16381* / D1Pas1* / Q62167* / Q62095* / DEAD-box helicase 3, Y-linked* / DEAD-box helicase 3, X-linked...ENSDARG0000002057386
ddx4 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 / Q61496* / Q9NQI0* / DEAD-box helicase 4* / ATP-dependent RNA helicase DDX4 *ENSDARG0000001437339
ddx59 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 / Q5T1V6* / Q9DBN9* / DEAD-box helicase 59* / Probable ATP-dependent RNA helicase DDX59 *ENSDARG0000002217721
ddx1 / DEAD (Asp-Glu-Ala-Asp) box helicase 1 / Q91VR5* / Q92499* / DEAD-box helicase 1* / ATP-dependent RNA helicase DDX1 *ENSDARG0000003211719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006413 translational initiation IBA
 biological_processGO:0007059 chromosome segregation IBA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye morphology , abnormal
eye decreased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism anatomical axis decreased length , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk curved ventral , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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