ENSDARG00000014943


Danio rerio

Features
Gene ID: ENSDARG00000014943
  
Biological name :kif23
  
Synonyms : kif23 / kinesin family member 23
  
Possible biological names infered from orthology : E9Q5G3 / Kinesin-like protein KIF23 / Q02241
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 20435821
Gene end: 20458840
  
Corresponding Affymetrix probe sets: Dr.8295.1.S1_at (Zebrafish Array)   Dr.8295.2.A1_at (Zebrafish Array)   NM_131355_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000143716
Ensembl peptide - ENSDARP00000026695
Ensembl peptide - ENSDARP00000119643
NCBI entrez gene - 30627     See in Manteia.
RefSeq - NM_131355
RefSeq Peptide - NP_571430
swissprot - A0A286Y967
swissprot - Q1LUF4
swissprot - Q9PUU5
ZFIN ID - ZDB-GENE-991019-4
Ensembl - ENSDARG00000014943
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KIF23ENSGALG00000008095Gallus gallus
 KIF23ENSG00000137807Homo sapiens
 Kif23ENSMUSG00000032254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kif20bb / kinesin family member 20Bb / KIF20B* / Q80WE4* / Q96Q89* / kinesin family member 20B* / Kinesin-like protein KIF20B *ENSDARG0000004011020
kif20ba / kinesin family member 20Ba / KIF20B* / Q80WE4* / Q96Q89* / kinesin family member 20B* / Kinesin-like protein KIF20B *ENSDARG0000007100920
zgc:56231ENSDARG0000001033219
kif18a / kinesin family member 18A / Q8NI77* / Q91WD7* / Kinesin-like protein KIF18A *ENSDARG0000000802218
kif19 / kinesin family member 19 / Kif19a* / Q2TAC6* / Q99PT9* / Kinesin-like protein KIF19 *ENSDARG0000005302618
kif20a / kinesin family member 20A / O95235* / P97329* / Kinesin-like protein KIF20A *ENSDARG0000004449118
si:dkey-26i13.8 / Gm4869*ENSDARG0000006260617
kif22 / kinesin family member 22 / Q14807* / Q3V300* / Kinesin-like protein KIF22 *ENSDARG0000010262417
KIF2A / zgc:103670 / O00139* / kinesin family member 2A*ENSDARG0000004357115
kif2c / kinesin family member 2C / Q922S8* / Q99661* / Kinesin-like protein KIF2C *ENSDARG0000007622814
CABZ01117348.1ENSDARG000001097702


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032384  Kinesin-like protein Kif23, Arf6-interacting domain
 IPR032924  Kinesin-like protein KIF23


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IMP
 biological_processGO:0000910 cytokinesis IEA
 biological_processGO:0000915 actomyosin contractile ring assembly IEA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0036089 cleavage furrow formation IMP
 biological_processGO:0040016 embryonic cleavage IMP
 biological_processGO:0047496 vesicle transport along microtubule IMP
 biological_processGO:0051256 mitotic spindle midzone assembly IBA
 biological_processGO:0072383 plus-end-directed vesicle transport along microtubule IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0032154 cleavage furrow IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IBA


Pathways (from Reactome)
Pathway description
Mitotic Telophase/Cytokinesis
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism necrotic , abnormal
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 ZFA:0001114 head head flat , abnormal
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 ZFA:0001115 trunk trunk necrotic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014943 kif23 / kinesin family member 23 / E9Q5G3* / Q02241* / Kinesin-like protein KIF23 *  / complex / reaction
 ENSDARG00000015460 racgap1 / Rac GTPase activating protein 1 / Q9H0H5* / Q9WVM1*  / reaction / complex
 ENSDARG00000058471 plk1 / polo-like kinase 1 (Drosophila) / P53350* / Q07832* / polo like kinase 1*  / reaction






 

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