ENSDARG00000015239


Danio rerio

Features
Gene ID: ENSDARG00000015239
  
Biological name :prpf19
  
Synonyms : pre-mRNA processing factor 19 / prpf19
  
Possible biological names infered from orthology : Q99KP6 / Q9UMS4
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 16287968
Gene end: 16301402
  
Corresponding Affymetrix probe sets: Dr.3564.1.S1_at (Zebrafish Array)   NM_201467_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000097371
NCBI entrez gene - 321544     See in Manteia.
RefSeq - NM_201467
RefSeq Peptide - NP_958875
swissprot - Q7ZV92
ZFIN ID - ZDB-GENE-030131-263
Ensembl - ENSDARG00000015239
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000036530Gallus gallus
 PRPF19ENSG00000110107Homo sapiens
 Prpf19ENSMUSG00000024735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prpf4 / PRP4 pre-mRNA processing factor 4 homolog (yeast) / O43172* / Q9DAW6* / pre-mRNA processing factor 4*ENSDARG0000006763920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000772  Ricin B, lectin domain
 IPR001680  WD40 repeat
 IPR003613  U box domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013915  Pre-mRNA-splicing factor 19
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000349 generation of catalytic spliceosome for first transesterification step IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IMP
 cellular_componentGO:0000974 Prp19 complex IBA
 cellular_componentGO:0071006 U2-type catalytic step 1 spliceosome IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA


Pathways (from Reactome)
Pathway description
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009248 neuron neuron increased sensitivity to irradiation , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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